| IED ID | IndEnz0002005466 |
| Enzyme Type ID | protease005466 |
| Protein Name |
Subtilisin-like serine protease Cla h 9.0101 EC 3.4.21.- Vacuolar serine protease allergen Cla h 9.0101 |
| Gene Name | |
| Organism | Davidiella tassiana (Mycosphaerella tassiana) (Cladosporium herbarum) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta dothideomyceta Dothideomycetes Dothideomycetidae Cladosporiales Cladosporiaceae Cladosporium Davidiella tassiana (Mycosphaerella tassiana) (Cladosporium herbarum) |
| Enzyme Sequence | MRGALAGLSLATLATASPVLVNSIHNDAAPIISASNAKEIADNYMIKFKDHVTQNLAAEHHGWVQDLHEKTQVAKTELRKRSQSPMVDDIFNGLKHTYNIAGGLMGYAGHFDEDVIEQIRRHPDVELVERDQEVHVLGSESEVEKNAPWGLARISHRDSLSFGTFNKYLYTEDGGEGVDVYVVDTGTNVDHVDFEGRASWGKTIPQGDADEDGNGHGTHCSGTVAGKKYGVAKKAHVKAVKVLRSNGSGSMSDVVKGVEYAAESHLEQVSITKKGKRKGFKGSTANMSLGGGKSPILDKAVNAAVDAGIHFAVAAGNDNADSCNYSPAAAENAVTVGASTLADERAYFSNYGKCNDIFAPGLNIQSTWIGSKYAVNTISGTSMASPHVAGLLAYLLSLQPAKDSAFAVADISPKKLKANLISIATVGALTDVPSNTANILAWNGGGESNYSAIVEKGGYKATHRPTMLEEIESEAKVASKKVYSEGDELAHKVAELTEKVEDLIAGELKDMFRELKRE |
| Enzyme Length | 518 |
| Uniprot Accession Number | B7ZK61 |
| Absorption | |
| Active Site | ACT_SITE 184; /note=Charge relay system; /evidence=ECO:0000255|PROSITE-ProRule:PRU01240; ACT_SITE 216; /note=Charge relay system; /evidence=ECO:0000255|PROSITE-ProRule:PRU01240; ACT_SITE 382; /note=Charge relay system; /evidence=ECO:0000255|PROSITE-ProRule:PRU01240 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.21.- |
| Enzyme Function | FUNCTION: Serine protease. {ECO:0000250|UniProtKB:Q9Y749}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Domain (2); Glycosylation (3); Propeptide (2); Region (1); Signal peptide (1); Site (1) |
| Keywords | Allergen;Direct protein sequencing;Glycoprotein;Hydrolase;IgE-binding protein;Protease;Serine protease;Signal;Zymogen |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..16; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 55,242 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |