Detail Information for IndEnz0002005511
IED ID IndEnz0002005511
Enzyme Type ID protease005511
Protein Name Leukocyte cysteine proteinase inhibitor 1
PLCPI
Stefin-D1
Gene Name
Organism Sus scrofa (Pig)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Laurasiatheria Artiodactyla Suina Suidae (pigs) Sus Sus scrofa (Pig)
Enzyme Sequence MESEEMLAGGLTEPRPATPEIQEIANKVKPQLEEKTNKTYEKFEAIIYRSQVVAGTNYYIKVHVGGNNYVHIRVFQSLPHQEDPLKLIGYQVDKTKDDELTGF
Enzyme Length 103
Uniprot Accession Number P35479
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Potent inhibitor of cathepsins L and S, and papain.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Modified residue (1); Motif (1); Region (1); Site (1)
Keywords Cytoplasm;Direct protein sequencing;Protease inhibitor;Reference proteome;Thiol protease inhibitor
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Cytoplasm.
Modified Residue MOD_RES 1; /note=Blocked amino end (Met); partial
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif MOTIF 51..55; /note=Secondary area of contact
Gene Encoded By
Mass 11,767
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda