| IED ID | IndEnz0002005535 |
| Enzyme Type ID | protease005535 |
| Protein Name |
Preflagellin peptidase PFP EC 3.4.23.52 |
| Gene Name | rrnAC2525 |
| Organism | Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui) |
| Taxonomic Lineage | cellular organisms Archaea Euryarchaeota Stenosarchaea group Halobacteria Halobacteriales Haloarculaceae Haloarcula Haloarcula marismortui Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui) |
| Enzyme Sequence | MLGSIPDLLRLVAVPVFGWAAYRDVKTRRVPNRTWTPLAALAVVLLLWDAYTVWTGPTAVGQRLFLIRVAISLGFVIPLSYGFWLIGGFGGADAKAFMLIAVLFPIYPVYYLPMPSVALPLQQTAIGVFSLTVLSNTVLAGVVYPLAVAAGNLARGRFSLAMFIGRPVAVPDVTEEYGRLLESPDGFDRGGLDLDALRMYLQWRGCSLADIRADPAQRRLPTSLPAVPNDPGDGSLATDGGDSASGDVAEPSANDIGADGMDHPDQIDDPWGAERFLDDIDHSAYGTSPQQLRDGLDVLVEQDEVWISPGIPFLVPMFAGLVVSLTYGDVLFSLLQAVGLA |
| Enzyme Length | 341 |
| Uniprot Accession Number | Q5UZH5 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Cleaves the signal peptide of 3 to 12 amino acids from the N-terminal of preflagellin, usually at Arg-Gly-|- or Lys-Gly-|-, to release flagellin.; EC=3.4.23.52; |
| DNA Binding | |
| EC Number | 3.4.23.52 |
| Enzyme Function | FUNCTION: Cleaves the N-terminal leader peptide from preflagellins. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Erroneous initiation (1); Region (1); Site (2); Topological domain (7); Transmembrane (6) |
| Keywords | Archaeal flagellum biogenesis;Cell membrane;Hydrolase;Membrane;Protease;Reference proteome;Transmembrane;Transmembrane helix |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 36,559 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |