| IED ID | IndEnz0002005554 |
| Enzyme Type ID | protease005554 |
| Protein Name |
Gamete and mating-type specific protein A EC 3.4.22.- |
| Gene Name | gmsA DDB_G0286015 |
| Organism | Dictyostelium discoideum (Slime mold) |
| Taxonomic Lineage | cellular organisms Eukaryota Amoebozoa Evosea Eumycetozoa Dictyostelia (dictyostelid cellular slime molds) Dictyosteliales Dictyosteliaceae Dictyostelium Dictyostelium discoideum (Slime mold) |
| Enzyme Sequence | MKLILVLLCLISTLFVVKGGLSPTEQQIIVSYHNKWRSSPIGPTPSTTIPALKWNATIAAALQSSLDKCDGKFSTMSQYGTNSEWQSWWTPNTYFNLNATLDNIQKGASFYDWNAKGCNSSANYNCQLWTYAVWSKSTSYGCAKTICPDKSEVSCSYYPAGGFKGVLPYTPKTTTPAPTTPAPTTPKPTTPAPTTPKPTTPAPTTPKPTTPAPTTPKPTTPAPTTPKPTTPAPTTPAPTSTLTVDWTSYQTPIRDQGQCGSCWAFASSAALESRYLIKYGTAQKSTLQLSNQNAVNCIASGCNGGWSGNYFNFFKTPGIAYEKDDPYKAVTGTSCITTSSVARFKYTNYGYTEKTKAALLAELKKGPVTIAVYVDSAFQNYKSGIYNSATKYTGINHLVLLVGYDQATDAYKIKNSWGSWWGESGYMRITASNDNLAIFAYNSYYPTF |
| Enzyme Length | 448 |
| Uniprot Accession Number | Q54ME1 |
| Absorption | |
| Active Site | ACT_SITE 262; /evidence=ECO:0000255|PROSITE-ProRule:PRU10088; ACT_SITE 397; /evidence=ECO:0000255|PROSITE-ProRule:PRU10088; ACT_SITE 415; /evidence=ECO:0000255|PROSITE-ProRule:PRU10088 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.22.- |
| Enzyme Function | FUNCTION: Thiol protease that seems to be involved in the sexual development. {ECO:0000269|PubMed:12963116}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Compositional bias (1); Domain (1); Glycosylation (3); Region (1); Signal peptide (1) |
| Keywords | Glycoprotein;Hydrolase;Protease;Reference proteome;Secreted;Signal;Thiol protease |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..19; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 15817229; 16815590; 21929567; |
| Motif | |
| Gene Encoded By | |
| Mass | 48,674 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |