| IED ID | IndEnz0002005616 |
| Enzyme Type ID | protease005616 |
| Protein Name |
Probable Xaa-Pro aminopeptidase AN0832 EC 3.4.11.9 Aminoacylproline aminopeptidase Prolidase |
| Gene Name | AN0832 |
| Organism | Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Eurotiales (green and blue molds) Aspergillaceae Aspergillus Aspergillus subgen. Nidulantes Emericella nidulans (Aspergillus nidulans) Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) |
| Enzyme Sequence | MRVSDPAKLDILPDDACEIRLTIAASECDKYPAKQHARKVASKLGVRDGLIYLVGKATINWGDSDQPRPFRQRRYFYYLSGVDEADCYLTYDIRNDLLTIYVPNFSLQHAIWMGPTLTVEEARQRYDADRFRYYAALRSDLNSWVDQYNKDSPIYVLHSSQKPEISAKELRSREVKDEYEIRMIRKANEISALAHRNILQNIHRMSNESEIEGLFLDTCVSHGAKNQSYEIIAGSGPNAAVLHYVKNDEPLNGRQLVCLDAGAEWNCYASDVTRTIPLGKDWPSSHAKDIYAIVEEMQEECIRRVKPGLRFRDLHELAHIIAIKGLQELGVLKAGTVEEIRRSGASSIFFPHGLGHHVGLEVHDVSEQPITANGHLSREFVPQMSTPLLQEGMVITIEPGVYFNKLALENSRSLPLAKYIDFDKAEQYIPVGGVRIEDDLLVTSTGYENLTMAPKGKEMLEILRGRSKQ |
| Enzyme Length | 469 |
| Uniprot Accession Number | Q5BF48 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide.; EC=3.4.11.9; |
| DNA Binding | |
| EC Number | 3.4.11.9 |
| Enzyme Function | FUNCTION: Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Metal binding (6) |
| Keywords | Aminopeptidase;Hydrolase;Manganese;Metal-binding;Metalloprotease;Protease;Reference proteome |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 53,150 |
| Kinetics | |
| Metal Binding | METAL 260; /note=Manganese 2; /evidence=ECO:0000250; METAL 271; /note=Manganese 1; /evidence=ECO:0000250; METAL 271; /note=Manganese 2; /evidence=ECO:0000250; METAL 398; /note=Manganese 1; /evidence=ECO:0000250; METAL 437; /note=Manganese 1; /evidence=ECO:0000250; METAL 437; /note=Manganese 2; /evidence=ECO:0000250 |
| Rhea ID | |
| Cross Reference Brenda |