| IED ID | IndEnz0002005627 |
| Enzyme Type ID | protease005627 |
| Protein Name |
Xaa-Pro aminopeptidase 2 EC 3.4.11.9 Aminoacylproline aminopeptidase II Aminopeptidase P II APP PEPP II X-Pro aminopeptidase II Xaa-Pro aminopeptidase II |
| Gene Name | pepP2 SCO1352 2SCG61.34c |
| Organism | Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) |
| Taxonomic Lineage | cellular organisms Bacteria Terrabacteria group Actinobacteria Actinomycetia (high G+C Gram-positive bacteria) Streptomycetales Streptomycetaceae Streptomyces Streptomyces albidoflavus group Streptomyces coelicolor Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) |
| Enzyme Sequence | MSNRRKNSLYPTLSAELSALMRTGWADTERHDLAPAEQAPYAALRRAALSARFPGERLVVPSGNLKVRSNDDTYPFRSYSGYVHMTGDQARDGALVLEPRPDGGHDAYCYQLPRDSRDDDEFWTGAHAELWTGRRRSLAESERVLGLPCRDVRTAAADLAAVSEVRTRIVRGIDPALEAAVTTDEERDAELEDALSDLRLVKDAWELGELRKAVDSTVRGFTDVVGELSRAVASSERWLEGTFFRRARLEGNAVGYGTICAAGEHATIMHWTDNDGPVRPGDLLLLDAGVETRSLYTADVTRTLPISGTFTPLQREVYDAVYEAQEAGIATVKPGAAYRDFHEAAQRHLAARLVEWGFIEGPAERAYELGLQRRFTMAGTGHMLGLDVHDCARARTEEYVEGVLEPGMCLTVEPGLYFQADDLTVPEEWRGIGVRIEDDLVVTEDGHENLSAGLPRSADEVEAWMARFAG |
| Enzyme Length | 470 |
| Uniprot Accession Number | P0A3Z3 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide.; EC=3.4.11.9; |
| DNA Binding | |
| EC Number | 3.4.11.9 |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Metal binding (7) |
| Keywords | Aminopeptidase;Hydrolase;Manganese;Metal-binding;Metalloprotease;Protease;Reference proteome |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 51,925 |
| Kinetics | |
| Metal Binding | METAL 287; /note=Manganese 2; /evidence=ECO:0000250; METAL 299; /note=Manganese 1; /evidence=ECO:0000250; METAL 299; /note=Manganese 2; /evidence=ECO:0000250; METAL 382; /note=Manganese 1; /evidence=ECO:0000250; METAL 413; /note=Manganese 1; /evidence=ECO:0000250; METAL 437; /note=Manganese 1; /evidence=ECO:0000250; METAL 437; /note=Manganese 2; /evidence=ECO:0000250 |
| Rhea ID | |
| Cross Reference Brenda |