| IED ID | IndEnz0002005641 |
| Enzyme Type ID | protease005641 |
| Protein Name |
Proteinase inhibitor CeKI Fragment |
| Gene Name | |
| Organism | Paubrasilia echinata (Pau Brasil) (Caesalpinia echinata) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids fabids Fabales Fabaceae Caesalpinioideae Caesalpinia clade Paubrasilia Paubrasilia echinata (Pau Brasil) (Caesalpinia echinata) |
| Enzyme Sequence | FVVETENQLMSQGGRYYILPVIYGKGGGLG |
| Enzyme Length | 30 |
| Uniprot Accession Number | P84795 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Potent inhibitor of serine proteases plasma kallikrein, plasmin and coagulation factor XIIa. Weak inhibitor of serine proteases trypsin and coagulation factor Xa. Does not inhibit the serine proteases chymotrypsin, elastase or thrombin. Inhibits kinin release from HMW-kininogen by kallikrein in vitro. {ECO:0000269|PubMed:15576329}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Non-terminal residue (1) |
| Keywords | Blood coagulation;Direct protein sequencing;Fibrinolysis;Hemostasis;Metalloenzyme inhibitor;Metalloprotease inhibitor;Protease inhibitor;Serine protease inhibitor |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 3,247 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |