| IED ID | IndEnz0002005704 |
| Enzyme Type ID | protease005704 |
| Protein Name |
Cathepsin B-like cysteine proteinase EC 3.4.22.- Antigen Sj31 |
| Gene Name | CATB |
| Organism | Schistosoma japonicum (Blood fluke) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Spiralia Lophotrochozoa Platyhelminthes Trematoda Digenea (flukes) Strigeidida Schistosomatoidea Schistosomatidae (blood flukes) Schistosoma Schistosoma japonicum (Blood fluke) |
| Enzyme Sequence | MLKIAVYIVSLFTFLEAHVTTRNNQRIEPLSDEMISFINEHPDAGWKADKSDRFHSLDDARILMGARKEDAEMKRNRRPTVDHHDLNVEIPSQFDSRKKWPHCKSISQIRDQSRCGSCWAFGAVEAMTDRICIQSGGGQSAELSALDLISCCKDCGDGCQGGFPGVAWDYWVKRGIVTGGSKENHTGCQPYPFPKCEHHTKGKYPACGTKIYKTPQCKQTCQKGYKTPYEQDKHYGDESYNVQNNEKVIQRDIMMYGPVEAAFDVYEDFLNYKSGIYRHVTGSIVGGHAIRIIGWGVEKRTPYWLIANSWNEDWGEKGLFRMVRGRDECSIESDVVAGLIKT |
| Enzyme Length | 342 |
| Uniprot Accession Number | P43157 |
| Absorption | |
| Active Site | ACT_SITE 118; /evidence=ECO:0000250; ACT_SITE 288; /evidence=ECO:0000250; ACT_SITE 308; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.22.- |
| Enzyme Function | FUNCTION: Thiol protease. Has a role as a digestive enzyme. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Disulfide bond (6); Propeptide (1); Signal peptide (1) |
| Keywords | Disulfide bond;Hydrolase;Protease;Signal;Thiol protease;Zymogen |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..17; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 38,796 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |