Detail Information for IndEnz0002005808
IED ID IndEnz0002005808
Enzyme Type ID protease005808
Protein Name Assembly protein G7
Gene Name G7L
Organism Variola virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox virus)
Taxonomic Lineage Viruses Varidnaviria Bamfordvirae Nucleocytoviricota Pokkesviricetes Chitovirales Poxviridae Chordopoxvirinae Orthopoxvirus Variola virus Variola virus (isolate Human/India/Ind3/1967) (VARV) (Smallpox virus)
Enzyme Sequence MAAEQRRSTIFDIVSKCIVQSVLRDISINSEYIESKAKQLCYCPASKKESVINGIYNCCESNIEIMDKEQLLKILDNLRCHSAHVCNATDFWRLYNSLKRFTHTTAFFNTCKPTILATLNTLITLILSNKLLYAAEMVEYLENQLDSSNKSMSQELAELLEMKYALINLVQYRILPMIIGEPIIVAGFSGKEPISNYSAEVERLMELPVKTDIVNTTYDFLARKGIDTSNNIAEYIAGLKIEEIEKVEKYLPEVISTIANSNIIKNKKSIFPANINDKQIMECSKMLDTSEKYSKGYKTDGAVTSPLTGNNTITTFIPISASDMQKFTILEYLYIMRVMANNVKKKNEGKNNGGVVMHINSPFKVINLPKC
Enzyme Length 371
Uniprot Accession Number P0DSU1
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Late protein which is a part of a large complex required for early virion morphogenesis. This complex participates in the formation of virosomes and the incorporation of virosomal contents into nascent immature virions (By similarity). {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Site (2)
Keywords Host cytoplasm;Phosphoprotein;Reference proteome;Virion
Interact With
Induction INDUCTION: Expressed in the late phase of the viral replicative cycle.
Subcellular Location SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000250}. Virion {ECO:0000250}. Note=Localizes in cytoplasmic virus factories and present in the virion core. {ECO:0000250}.
Modified Residue
Post Translational Modification PTM: Phosphorylated on serines by F10 kinase, phosphorylation state is regulated by H1 phosphatase. {ECO:0000250}.; PTM: Undergoes proteolytic processing during morphogenesis, probably required for the transformation of immature virions (IV) into mature virions (MV). {ECO:0000250}.
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 41,922
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda