| IED ID | IndEnz0002005832 |
| Enzyme Type ID | protease005832 |
| Protein Name |
Dipeptidyl peptidase 3 EC 3.4.14.4 Dipeptidyl aminopeptidase III Dipeptidyl arylamidase III Dipeptidyl peptidase III DPP III |
| Gene Name | dpp3-1 DDB_G0273471; dpp3-2 DDB_G0273563 |
| Organism | Dictyostelium discoideum (Slime mold) |
| Taxonomic Lineage | cellular organisms Eukaryota Amoebozoa Evosea Eumycetozoa Dictyostelia (dictyostelid cellular slime molds) Dictyosteliales Dictyosteliaceae Dictyostelium Dictyostelium discoideum (Slime mold) |
| Enzyme Sequence | MSVPSSVIENHLVPKEIPVYRLNARESFNLLTEKEQLYAHHISVACWWGSKICLGQTSIESGPIFNLFQNLFSIQNLKSTVVPNIVSEEEYSDLLSYAATFYGNMGNYLSFGDSKFIPRISKEKLQLIINKVNDNKVNEYWGKCSELMYSLDKQVRELGIDGNGISTYYSPNITKVEIEKVQKFMDSKSISPYNTRLFKVSENNYNLLIASASTSTPTVSHQFDGYTINIVYGDWNKNLTKVVDNLKLALPYAANENQTNMLKKYIDSFYSGSIDDHKDSQRWWIKDISPAVETNIGFIESYRDPYGVRGEWEGFVSMVNKEMSLKFGKLTDNATTFLSKLPWDKSFEKEKFNKPDFTSLEVLTFATTGIPAGINLSNYDDIRQTEGFKNVSLGNVIAARKDEYVTFIQESDQKLFNELSTEAFELQVGIHELYGHGSGKLFTTDANGNVNFKVGEVINPLTNKPIDPKTEVYKFGETYDSVFKSLGSPMEECRAECCGIYLSPDEKILELFGFTDPKKAEDVYYVNWLIMARAGVCALEFYSPPSEGAPGKWRQAHMQARYCILTTFLRSGIVTLDKTADDVIVKLDKSKIRGIGVKAVGDFLNRLMVYKATANIDASIKLFDEYTHVNEEFLAIRDIVLAKKKPRKVFVQAHTYLNSNGKVCLQDFDDSTQGMIDSMITRFGKDDSDML |
| Enzyme Length | 691 |
| Uniprot Accession Number | Q557H1 |
| Absorption | |
| Active Site | ACT_SITE 432; /evidence=ECO:0000250|UniProtKB:O55096 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Release of an N-terminal dipeptide from a peptide comprising four or more residues, with broad specificity. Also acts on dipeptidyl 2-naphthylamides.; EC=3.4.14.4; |
| DNA Binding | |
| EC Number | 3.4.14.4 |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (1); Chain (1); Metal binding (3) |
| Keywords | Aminopeptidase;Cytoplasm;Hydrolase;Metal-binding;Metalloprotease;Protease;Reference proteome;Zinc |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 22120990; |
| Motif | |
| Gene Encoded By | |
| Mass | 78,274 |
| Kinetics | |
| Metal Binding | METAL 431; /note=Zinc; catalytic; /evidence=ECO:0000250|UniProtKB:Q9NY33; METAL 436; /note=Zinc; catalytic; /evidence=ECO:0000250|UniProtKB:Q9NY33; METAL 492; /note=Zinc; catalytic; /evidence=ECO:0000250|UniProtKB:Q9NY33 |
| Rhea ID | |
| Cross Reference Brenda |