| IED ID |
IndEnz0002005933 |
| Enzyme Type ID |
protease005933 |
| Protein Name |
Guamerin
|
| Gene Name |
|
| Organism |
Hirudo nipponia (Korean blood-sucking leech) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Metazoa
Eumetazoa
Bilateria
Protostomia
Spiralia
Lophotrochozoa
Annelida
Clitellata
Hirudinea (leeches)
Hirudinida
Hirudiniformes
Hirudinidae
Hirudo
Hirudo nipponia (Korean blood-sucking leech)
|
| Enzyme Sequence |
VDENAEDTHGLCGEKTCSPAQVCLNNECACTAIRCMIFCPNGFKVDENGCEYPCTCA |
| Enzyme Length |
57 |
| Uniprot Accession Number |
P46443 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: Inhibits mammalian elastases. {ECO:0000269|PubMed:18155725}. |
| Temperature Dependency |
|
| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Beta strand (5); Chain (1); Disulfide bond (5); Domain (1); Mutagenesis (1); Site (1) |
| Keywords |
3D-structure;Direct protein sequencing;Disulfide bond;Protease inhibitor;Secreted;Serine protease inhibitor |
| Interact With |
|
| Induction |
|
| Subcellular Location |
SUBCELLULAR LOCATION: Secreted. |
| Modified Residue |
|
| Post Translational Modification |
|
| Signal Peptide |
|
| Structure 3D |
X-ray crystallography (1) |
| Cross Reference PDB |
3BG4;
|
| Mapped Pubmed ID |
- |
| Motif |
|
| Gene Encoded By |
|
| Mass |
6,123 |
| Kinetics |
|
| Metal Binding |
|
| Rhea ID |
|
| Cross Reference Brenda |
|