| IED ID | IndEnz0002005936 |
| Enzyme Type ID | protease005936 |
| Protein Name |
Fibrinolytic enzyme EC 3.4.-.- CMase Fragment |
| Gene Name | |
| Organism | Cordyceps militaris (Caterpillar fungus) (Clavaria militaris) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta sordariomyceta Sordariomycetes Hypocreomycetidae Hypocreales Cordycipitaceae Cordyceps Cordyceps militaris (Caterpillar fungus) (Clavaria militaris) |
| Enzyme Sequence | IVGGVSVAIE |
| Enzyme Length | 10 |
| Uniprot Accession Number | P85318 |
| Absorption | |
| Active Site | |
| Activity Regulation | ACTIVITY REGULATION: Activated by Mg(2+) and Fe(2+) ions. Inhibited by Cu(2+) ions and EDTA. Activity is unaffected by Ca(2+), Ba(2+), Zn(2+), K(+) and Mn(2+) ions. {ECO:0000269|Ref.1}. |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.-.- |
| Enzyme Function | FUNCTION: Hydrolyzes fibrin. {ECO:0000269|Ref.1}. |
| Temperature Dependency | BIOPHYSICOCHEMICAL PROPERTIES: Temperature dependence: Optimum temperature is 25 degrees Celsius. Active between 15 and 45 degrees Celsius, however activity rapidly decreases after 1 hour incubation at temperatures above 40 degrees Celsius. {ECO:0000269|Ref.1}; |
| PH Dependency | BIOPHYSICOCHEMICAL PROPERTIES: pH dependence: Optimum pH is 6.0. Active from pH 5.0 to 8.0 at 37 degrees Celsius, above pH 8.0 stability decreases rapidly. {ECO:0000269|Ref.1}; |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Non-terminal residue (1) |
| Keywords | Direct protein sequencing;Hydrolase;Protease;Secreted |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted, extracellular space {ECO:0000269|Ref.1}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 943 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |