| IED ID | IndEnz0002005957 |
| Enzyme Type ID | protease005957 |
| Protein Name |
Trypsin Blo t 3 EC 3.4.21.4 Mite allergen Blo t 3 allergen Blo t 3 |
| Gene Name | |
| Organism | Blomia tropicalis (Mite) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Panarthropoda Arthropoda Chelicerata Arachnida Acari Acariformes Sarcoptiformes Astigmata Glycyphagoidea Echimyopodidae Blomia Blomia tropicalis (Mite) |
| Enzyme Sequence | MKVLVLFCLVSLAAAGPLKDALNKAQVDAFYAEGYIVDGSNAADGDAPYQVSLQRTSHFCGGSIIADNYILTAAHCIQGLSASSLTIRYNTLRHNSGGLTVKASRIIGHEKYDSNTIDNDIALIQTASKMSTGTTNAQAIKLPEQGSDPKASSEVLITGWGTLSSGASSLPTKLQKVTVPIVDRKTCNANYGAVGADITDNMFCAGILNVGGKDACQGDSGGPVAANGVLVGAVSWGYGCAQAKYPGVYTRVGNYISWIKGKGVPV |
| Enzyme Length | 266 |
| Uniprot Accession Number | A1KXI1 |
| Absorption | |
| Active Site | ACT_SITE 75; /note=Charge relay system; /evidence=ECO:0000255|PROSITE-ProRule:PRU00274; ACT_SITE 120; /note=Charge relay system; /evidence=ECO:0000255|PROSITE-ProRule:PRU00274; ACT_SITE 220; /note=Charge relay system; /evidence=ECO:0000255|PROSITE-ProRule:PRU00274 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.; EC=3.4.21.4; Evidence={ECO:0000250|UniProtKB:P35030}; |
| DNA Binding | |
| EC Number | 3.4.21.4 |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Disulfide bond (3); Domain (1); Propeptide (1); Sequence conflict (4); Signal peptide (1); Site (1) |
| Keywords | Allergen;Disulfide bond;Hydrolase;Protease;Secreted;Serine protease;Signal;Zymogen |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:12752596}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..15; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 27,555 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |