| IED ID | IndEnz0002005992 |
| Enzyme Type ID | protease005992 |
| Protein Name |
Carboxypeptidase Y homolog ARB_05721 EC 3.4.16.5 |
| Gene Name | ARB_05721 |
| Organism | Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Onygenales Arthrodermataceae (dermatophytes) Trichophyton Arthroderma benhamiae (Trichophyton mentagrophytes) Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes) |
| Enzyme Sequence | MELYLNMLSFWYILLATSFFGPSQAVYQAPLSVDESQKVTIEEGFQIFTSKHSPQHSIRIKKQDGSICDAHSAQYTGWLDIGPKHLFFWYFESQNDPENDPLTLWMTGGPGYSSMLGMLEEVGPCLVNEYGNGTKYNPWGWSKKSSMLFVDQPVGVGFSYGDEGHDIPNDSYLAAVDMHRFLQLFISEVFPNKLNSPFHISGESYGGHYIPYLGAQIVRQNKLYPNEPQVQLKSCLIGNGCMSHMHTTFGYWETLCTTNPGVEKPIFNETRCDIMAKNMPRCMKVAEVCRRNPDPAICLSAQSVCDEGITGLYNKESDVKGGRNRFDITTPCQADDICYVQGLHLQNYLNTKLVWDALSPPKEVKEYKFASKNVEHAFGLTSDSMVPSTEEVEFLLSNQIHIMSYQGNLDLACNTAGNLKWMHDIPWKGQAELSSKALVPWKSVLASTGKNETVGRMKEVKIRVTDSATFATRYAFVTVDNAGHMVPQDRPDVAFDLMNRWISGETFV |
| Enzyme Length | 508 |
| Uniprot Accession Number | D4ANB6 |
| Absorption | |
| Active Site | ACT_SITE 204; /evidence=ECO:0000250|UniProtKB:P00729; ACT_SITE 410; /evidence=ECO:0000250|UniProtKB:P08819; ACT_SITE 484; /evidence=ECO:0000250|UniProtKB:P00729 |
| Activity Regulation | |
| Binding Site | BINDING 413; /note=Substrate; /evidence=ECO:0000250|UniProtKB:P00729; BINDING 485; /note=Substrate; /evidence=ECO:0000250|UniProtKB:P00729 |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Release of a C-terminal amino acid with broad specificity.; EC=3.4.16.5; Evidence={ECO:0000250|UniProtKB:P00729}; |
| DNA Binding | |
| EC Number | 3.4.16.5 |
| Enzyme Function | FUNCTION: Involved in degradation of small peptides. {ECO:0000250|UniProtKB:P00729}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Binding site (2); Chain (1); Disulfide bond (3); Glycosylation (4); Signal peptide (1) |
| Keywords | Carboxypeptidase;Disulfide bond;Glycoprotein;Hydrolase;Protease;Reference proteome;Secreted;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:21919205}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..25; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 57,171 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |