| IED ID | IndEnz0002005995 |
| Enzyme Type ID | protease005995 |
| Protein Name |
Carboxypeptidase Y homolog A EC 3.4.16.5 |
| Gene Name | cpyA SS1G_12500 |
| Organism | Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) (White mold) (Whetzelinia sclerotiorum) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta sordariomyceta Leotiomycetes Helotiales Sclerotiniaceae Sclerotinia Sclerotinia sclerotiorum (White mold) (Whetzelinia sclerotiorum) Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) (White mold) (Whetzelinia sclerotiorum) |
| Enzyme Sequence | MKLLASTVLMGAAAASIAPQQQVLKNPFQSASKPISEAWSKSMESLNHLTDSMKDMTSEAKAVWDEVSTLFPEAMDRATFFQQPKPHTRKPDTAWDYVVKGADIQNVWVENSKGEKEREIDGKLEKYNMRAKKVDPTKLGVDKVKQYSGYLDDEENDKHLFYWFFESRNDPKNDPVVLWLNGGPGCSSLTGLFLELGPASIDKNGKLHNNPYSWNANASVIFLDQPVNVGYSYSGGSVSNTIAAGKDVYALLTLFFKQFPEYAKQDFHIAGESYAGHYIPVFTHEILSHKKRNINLKSVLIGNGLTDGLTQYEHYRPMACGEGGYPAVLDSSECKAMDNALPRCQSLIQSCYDSESVWSCVPASIYCNNAMMGPYQRTGQNVYDIRGKCEDSSNLCYSALGWISDYLNQAAVQKELGVEVSSYDSCNFDINRNFLFQGDWMQPFHRLVPDILEQIPVLIYAGDADFICNWLGNQAWTEALEWPGQKGFNAAKTKDLQLENGHKTGTFKSSGNFTFARIFGAGHMVPMDQPEASLDFLNKWLNDYTL |
| Enzyme Length | 546 |
| Uniprot Accession Number | A7F4H5 |
| Absorption | |
| Active Site | ACT_SITE 273; /evidence=ECO:0000250; ACT_SITE 465; /evidence=ECO:0000250; ACT_SITE 523; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Release of a C-terminal amino acid with broad specificity.; EC=3.4.16.5; Evidence={ECO:0000255|PROSITE-ProRule:PRU10074, ECO:0000255|PROSITE-ProRule:PRU10075}; |
| DNA Binding | |
| EC Number | 3.4.16.5 |
| Enzyme Function | FUNCTION: Vacuolar carboxypeptidase involved in degradation of small peptides. Digests preferentially peptides containing an aliphatic or hydrophobic residue in P1' position, as well as methionine, leucine or phenylalanine in P1 position of ester substrate (By similarity). {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Disulfide bond (5); Glycosylation (2); Propeptide (1); Signal peptide (1) |
| Keywords | Carboxypeptidase;Disulfide bond;Glycoprotein;Hydrolase;Protease;Reference proteome;Signal;Vacuole;Zymogen |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Vacuole {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..17; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 61,151 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |