| IED ID | IndEnz0002006004 |
| Enzyme Type ID | protease006004 |
| Protein Name |
Executioner caspase EC 3.4.22.- |
| Gene Name | ORF73 |
| Organism | Spodoptera frugiperda ascovirus 1a (SfAV-1a) |
| Taxonomic Lineage | Viruses Varidnaviria Bamfordvirae Nucleocytoviricota Megaviricetes Pimascovirales Ascoviridae Ascovirus Spodoptera frugiperda ascovirus 1a (SfAV-1a) |
| Enzyme Sequence | MSICYYDTVGREKRLLIINQRALALPNRTISSDGTCCDGDEYLLVDTFTKLNFKVQTIRNASKIVLETTVRNYIEKNVKRVACYFVVVLNDGNDADTILTTDGTYSLSELYALFTLYTVRAIPKVFLIQSCLGAKIDRSHCDRASCQCDQEEDAHPTSVCHDIFVNTVRRVIHACSRKSNGSTTTTETKCSDVATVVLTSPHTEETIIVYLRIEAYLRYGDTKCGCFMIEKFCKNLIKYGTRSSVHTTITMVQNEMQITDPKHVPIVQMNCTKLLFLGDENHIIMEEY |
| Enzyme Length | 288 |
| Uniprot Accession Number | Q5K5C1 |
| Absorption | |
| Active Site | ACT_SITE 131 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.22.- |
| Enzyme Function | FUNCTION: May induce host cell apoptosis and contribute of the establishment of a special cell cleavage process in which apoppotic bodies are rescued by the virus and differentiate to form large vesicles in which virion assembles. {ECO:0000269|PubMed:15933068}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (1); Chain (1) |
| Keywords | Apoptosis;Hydrolase;Protease;Reference proteome;Thiol protease |
| Interact With | |
| Induction | INDUCTION: Synthesized 9 hours after infection of cells ex vivo. |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 32,639 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |