| IED ID | IndEnz0002006009 |
| Enzyme Type ID | protease006009 |
| Protein Name |
Capsid protein Coat protein CP VP1 |
| Gene Name | ORF2 |
| Organism | Canine calicivirus (strain 48) (CaCV) |
| Taxonomic Lineage | Viruses Riboviria Orthornavirae Pisuviricota Pisoniviricetes Picornavirales Caliciviridae Vesivirus unclassified Vesivirus Canine vesivirus Canine calicivirus (strain 48) (CaCV) |
| Enzyme Sequence | MARYLELNPQNYSDEEYDYDSYNPFPNFEKNLASHYGTDFVPRINLDDFFLDDEDFEFCDDPLNCCFPDYLASLGEEEFIYEGDEPYIVLKHQLVSSTMWDDGTFTYPILPPFKTSSISYFLPKPGEVLHRCLMAVAKGMDPDLQVAVGTEFQFRAESDSSHPPDITTEDQGTVVATGPQPSAPAMATLATAATGTMPEEWKNFFSYYTTINWATTDETGKVLFVQNLAPRMNPFLDHIAKMYTGWSGSMEVRFTISGSGVFGGKVAAVLVPPGISTEGGTNLLQFPHVLVDARQTEPVIFTIPDIRTQLWHDMHDTSTSHLVILVYNDLVNPFQGGENGTSCTITVETRGGTDFEFHLLKPPTRKMIFGADPSRLIPRRSQFWEGNRLPGVITSFVCLPRMFQANRHFDCKRQTFGWSRPVHKGIEVRVDATNKDAANTTDIGIHVVTARNAIKSDIPDGWPDYYRTGEQVYNNTTQTFQEVKESVMGSAVPDSTATAMTWHHLPTVVFGHGTAVGSKTTNSKVLSGNFYAIGNFDQSGNIKLYPSYWIAKEQSAGGAPIGAYEDMVKRIDVLPTAQTTGGNFPVAFVSKFASSHNGNGVSVYNSQILTTSALLAQDVYDIGPNALAVFKIKGSGGYWFDLGISADGFSYVGGGNLNFSSLQFPLEATYVGMASLHNKLQYNLGGSATTL |
| Enzyme Length | 691 |
| Uniprot Accession Number | O72120 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Capsid protein self assembles to form an icosahedral capsid with a T=3 symmetry, about 38 nm in diameter, and consisting of 180 capsid proteins. A smaller form of capsid with a diameter of 23 nm might be capsid proteins assembled as icosahedron with T=1 symmetry. The capsid encapsulate the genomic RNA and VP2 proteins. Attaches virion to target cells by binding to specific cellular receptor. Once attached, the virion is endocytosed. Acidification of the endosome induces conformational change of capsid protein thereby injecting virus genomic RNA into host cytoplasm (By similarity). {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Mutagenesis (2); Propeptide (1); Site (1) |
| Keywords | Capsid protein;Host cytoplasm;T=3 icosahedral capsid protein;Virion |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Virion. Host cytoplasm {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | PTM: Cleaved by virus calcivirin to produce mature capsid protein. {ECO:0000250}. |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 76,181 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |