| IED ID |
IndEnz0002006080 |
| Enzyme Type ID |
protease006080 |
| Protein Name |
Protein masquerade
|
| Gene Name |
mas c-SPH79 SPH79 CG15002 |
| Organism |
Drosophila melanogaster (Fruit fly) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Metazoa
Eumetazoa
Bilateria
Protostomia
Ecdysozoa
Panarthropoda
Arthropoda
Mandibulata
Pancrustacea
Hexapoda
Insecta
Dicondylia
Pterygota (winged insects)
Neoptera
Endopterygota
Diptera
Brachycera
Muscomorpha
Eremoneura
Cyclorrhapha
Schizophora
Acalyptratae
Ephydroidea
Drosophilidae (pomace flies)
Drosophilinae
Drosophilini
Drosophila (fruit flies)
Sophophora
melanogaster group
melanogaster subgroup
Drosophila melanogaster (Fruit fly)
|
| Enzyme Sequence |
MPRHSSTMSRLVLPLIFSILLVSKPSPSQAQDESLAGSFLSGLLDTITSTADSKDCPGVCVHTLATLICYEVLDDVACPSPSMKCCIENAPAGKNATAVRATTTPKTTTTASTTTTQRTTTTVATTSTTKRTTTTSTTPKPKPKPQTKRPATSSTTKATVATTKKPSTTKKVATAKPKDKEEATKADDANKDCTGVCVADRIAEYCEAYLTSDGLCKEGTKCCVSLDEYSNGKLPKDIYIPAKHMSNLKPNQTLSEKSAPAKSSSTSTTSTTTTTSTTTTPEPARINNSSPKPTKHKKHPTTTTTEAAEEEEEQETEEDGEEEEPPLSNKLKSGQGQGQVLKECEGECMNGIFAIFCDDIDSDAFCPGEESCCVTGGASEATPSSKAPPTKPAIKHAPKPAAKPARPASPPPAPPSSTSGGGGGGDFLSQIISFAESTLNSPSPPPPPPQAPIQVPRCPGFCLLNIMAAFCERPSVLVSTPTTCAKGSVCCDNSRAGAPKPKLPPPTPSPTASPTAPPYVLPNTPSPDPREECPGSCIVSLLSFTCFKNAEMTDLFRCKRSGQICCAPKSKILEKQQFQTRNDTAYYPAPPPPPIGPPQAYPPQTPPYSYMNNPPPQGPPPQMAPHHPNPYQPPPPAPNYADYYPVSGPGLPPQPQPPMTTPPTTTTTTTTPRPHVYSKYVCGVKGTLRTGRSQALSFVSYARAKYGVQRTARQMTSAAGYSPNFNKSNERLVLGSAIVPIQIHNDKLGDLVESSSLQSNQLRSYHNHQAQADQPDLVYPEYYQQRSLYGLQSNFSGRRRARVVGGEDGENGEWCWQVALINSLNQYLCGAALIGTQWVLTAAHCVTNIVRSGDAIYVRVGDYDLTRKYGSPGAQTLRVATTYIHHNHNSQTLDNDIALLKLHGQAELRDGVCLVCLPARGVSHAAGKRCTVTGYGYMGEAGPIPLRVREAEIPIVSDTECIRKVNAVTEKIFILPASSFCAGGEEGHDACQGDGGGPLVCQDDGFYELAGLVSWGFGCGRQDVPGVYVKTSSFIGWINQIISVNNL |
| Enzyme Length |
1047 |
| Uniprot Accession Number |
Q9VZH2 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: In embryogenesis, has a role in somatic muscle attachment and in the development of axonal pathways probably by stabilizing cell-matrix adhesion and/or by acting as a competitive antagonist of serine proteases. {ECO:0000269|PubMed:7851790, ECO:0000269|PubMed:8817456}. |
| Temperature Dependency |
|
| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Alternative sequence (1); Chain (1); Compositional bias (7); Disulfide bond (20); Erroneous initiation (1); Glycosylation (6); Region (11); Sequence conflict (7); Signal peptide (1) |
| Keywords |
Alternative splicing;Cell projection;Developmental protein;Disulfide bond;Glycoprotein;Reference proteome;Repeat;Secreted;Serine protease homolog;Signal |
| Interact With |
|
| Induction |
|
| Subcellular Location |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:7851790}. Cell projection, axon {ECO:0000269|PubMed:7851790, ECO:0000269|PubMed:8817456}. Note=Localizes to vesicle-like structures in epidermal cells. {ECO:0000305|PubMed:7851790, ECO:0000305|PubMed:8817456}. |
| Modified Residue |
|
| Post Translational Modification |
PTM: Proteolytically cleaved and thereafter secreted. {ECO:0000269|PubMed:7851790}. |
| Signal Peptide |
SIGNAL 1..30; /evidence=ECO:0000255 |
| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
10529807;
10961941;
11035778;
11915949;
12505997;
12508226;
12568721;
15032585;
15501232;
16740481;
17996400;
20220848;
20371351;
20379222;
21074052;
21350018;
22135405;
23071443;
23699410;
23972280;
25312911;
26453810;
28067623;
3004962;
30367934;
32019873;
9754871;
|
| Motif |
|
| Gene Encoded By |
|
| Mass |
111,564 |
| Kinetics |
|
| Metal Binding |
|
| Rhea ID |
|
| Cross Reference Brenda |
|