| IED ID | IndEnz0002006141 |
| Enzyme Type ID | protease006141 |
| Protein Name |
Retrovirus-related Pol polyprotein from transposon RE2 Retro element 2 AtRE2 Includes: Protease RE2 EC 3.4.23.- ; Reverse transcriptase RE2 EC 2.7.7.49 ; Endonuclease RE2 |
| Gene Name | RE2 At4g02960 T4I9.16 |
| Organism | Arabidopsis thaliana (Mouse-ear cress) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis Arabidopsis thaliana (Mouse-ear cress) |
| Enzyme Sequence | MATHAEEIVLVNTNILNVNMSNVTKLTSTNYLMWSRQVHALFDGYELAGFLDGSTPMPPATIGTDAVPRVNPDYTRWRRQDKLIYSAILGAISMSVQPAVSRATTAAQIWETLRKIYANPSYGHVTQLRFITRFDQLALLGKPMDHDEQVERVLENLPDDYKPVIDQIAAKDTPPSLTEIHERLINRESKLLALNSAEVVPITANVVTHRNTNTNRNQNNRGDNRNYNNNNNRSNSWQPSSSGSRSDNRQPKPYLGRCQICSVQGHSAKRCPQLHQFQSTTNQQQSTSPFTPWQPRANLAVNSPYNANNWLLDSGATHHITSDFNNLSFHQPYTGGDDVMIADGSTIPITHTGSASLPTSSRSLDLNKVLYVPNIHKNLISVYRLCNTNRVSVEFFPASFQVKDLNTGVPLLQGKTKDELYEWPIASSQAVSMFASPCSKATHSSWHSRLGHPSLAILNSVISNHSLPVLNPSHKLLSCSDCFINKSHKVPFSNSTITSSKPLEYIYSDVWSSPILSIDNYRYYVIFVDHFTRYTWLYPLKQKSQVKDTFIIFKSLVENRFQTRIGTLYSDNGGEFVVLRDYLSQHGISHFTSPPHTPEHNGLSERKHRHIVEMGLTLLSHASVPKTYWPYAFSVAVYLINRLPTPLLQLQSPFQKLFGQPPNYEKLKVFGCACYPWLRPYNRHKLEDKSKQCAFMGYSLTQSAYLCLHIPTGRLYTSRHVQFDERCFPFSTTNFGVSTSQEQRSDSAPNWPSHTTLPTTPLVLPAPPCLGPHLDTSPRPPSSPSPLCTTQVSSSNLPSSSISSPSSSEPTAPSHNGPQPTAQPHQTQNSNSNSPILNNPNPNSPSPNSPNQNSPLPQSPISSPHIPTPSTSISEPNSPSSSSTSTPPLPPVLPAPPIIQVNAQAPVNTHSMATRAKDGIRKPNQKYSYATSLAANSEPRTAIQAMKDDRWRQAMGSEINAQIGNHTWDLVPPPPPSVTIVGCRWIFTKKFNSDGSLNRYKARLVAKGYNQRPGLDYAETFSPVIKSTSIRIVLGVAVDRSWPIRQLDVNNAFLQGTLTDEVYMSQPPGFVDKDRPDYVCRLRKAIYGLKQAPRAWYVELRTYLLTVGFVNSISDTSLFVLQRGRSIIYMLVYVDDILITGNDTVLLKHTLDALSQRFSVKEHEDLHYFLGIEAKRVPQGLHLSQRRYTLDLLARTNMLTAKPVATPMATSPKLTLHSGTKLPDPTEYRGIVGSLQYLAFTRPDLSYAVNRLSQYMHMPTDDHWNALKRVLRYLAGTPDHGIFLKKGNTLSLHAYSDADWAGDTDDYVSTNGYIVYLGHHPISWSSKKQKGVVRSSTEAEYRSVANTSSELQWICSLLTELGIQLSHPPVIYCDNVGATYLCANPVFHSRMKHIALDYHFIRNQVQSGALRVVHVSTHDQLADTLTKPLSRVAFQNFSRKIGVIKVPPSCGGVLRI |
| Enzyme Length | 1456 |
| Uniprot Accession Number | Q9ZT94 |
| Absorption | |
| Active Site | ACT_SITE 313; /note=For protease activity; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339, Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560, ChEBI:CHEBI:173112; EC=2.7.7.49; |
| DNA Binding | |
| EC Number | 3.4.23.-; 2.7.7.49 |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (1); Chain (1); Compositional bias (6); Domain (2); Erroneous gene model prediction (2); Metal binding (2); Natural variant (1); Region (3); Sequence conflict (6); Zinc finger (1) |
| Keywords | Aspartyl protease;DNA integration;DNA recombination;Endonuclease;Hydrolase;Magnesium;Metal-binding;Nuclease;Protease;Reference proteome;Transferase;Zinc;Zinc-finger |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 162,636 |
| Kinetics | |
| Metal Binding | METAL 509; /note=Magnesium; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU00457; METAL 571; /note=Magnesium; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU00457 |
| Rhea ID | RHEA:22508 |
| Cross Reference Brenda |