| IED ID | IndEnz0002006343 |
| Enzyme Type ID | protease006343 |
| Protein Name |
U21-ctenitoxin-Pn1a U21-CNTX-Pn1a EC 3.4.21.- Proteinase PN47 |
| Gene Name | |
| Organism | Phoneutria nigriventer (Brazilian armed spider) (Ctenus nigriventer) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Panarthropoda Arthropoda Chelicerata Arachnida Araneae (spiders) Araneomorphae Entelegynae RTA clade Lycosoidea Ctenidae (wandering spiders) Phoneutria Phoneutria nigriventer (Brazilian armed spider) (Ctenus nigriventer) |
| Enzyme Sequence | IVYGTVTTPGKYPWMVSIHERVKDVMKQACGGAILNENWIVTAAHCFDQPIILKDYEVYVGIVSWLHKNAPTVQKFQLSKIIIHDKYVKDGFANDIALIKTATPIDIKGSKYGVNGICFPSGATDPSGEATVIGWGMIRGGGPISAELRQVTLPLVPWQKCKQIYGHPDSEFEYIQVVPSMLCAGGNGKDACQFDSGGPLFQYDKKGVATLIGTVANGADCAYAHYPGMYMKVSAFRSWMDKVMT |
| Enzyme Length | 245 |
| Uniprot Accession Number | P84033 |
| Absorption | |
| Active Site | ACT_SITE 45; /note=Charge relay system; /evidence=ECO:0000255; ACT_SITE 95; /note=Charge relay system; /evidence=ECO:0000255; ACT_SITE 196; /note=Charge relay system; /evidence=ECO:0000255 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.21.- |
| Enzyme Function | FUNCTION: Protease. Hydrolyzes gelatin and succinyl casein. {ECO:0000269|PubMed:16278100}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Disulfide bond (3); Domain (1) |
| Keywords | Direct protein sequencing;Disulfide bond;Hydrolase;Protease;Secreted;Serine protease |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:16278100}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 26,776 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |