Detail Information for IndEnz0002006371
IED ID IndEnz0002006371
Enzyme Type ID protease006371
Protein Name Neutrophil elastase 2B
EC 3.4.21.-
Proteinase 2B
Fragments
Gene Name
Organism Equus caballus (Horse)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Laurasiatheria Perissodactyla (odd-toed ungulates) Equidae (horses) Equus Equus Equus caballus (Horse)
Enzyme Sequence IVGGRPARPHAWPFMASLQRRGGHFCGATLIMGWGQLGTNRPLPSVLQELNVTVVTAGICFGDSGGPLVCNGL
Enzyme Length 73
Uniprot Accession Number P37358
Absorption
Active Site ACT_SITE 64; /note=Charge relay system
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.21.-
Enzyme Function FUNCTION: May be involved in the degradation of connective tissue in chronic lung disease.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (1); Chain (1); Domain (1); Non-adjacent residues (2)
Keywords Direct protein sequencing;Hydrolase;Protease;Reference proteome;Serine protease
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 7,615
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda