| IED ID | IndEnz0002006381 |
| Enzyme Type ID | protease006381 |
| Protein Name |
Antihemorrhagic factor cHLP-A Chinese mamushi HSF-like protein A |
| Gene Name | |
| Organism | Gloydius brevicaudus (Korean slamosa snake) (Agkistrodon halys brevicaudus) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Sauropsida Sauria (diapsids) Lepidosauria (lepidosaurs) Squamata (squamates) Bifurcata (split-tongued squamates) Unidentata Episquamata Toxicofera Serpentes (snakes) Colubroidea Viperidae Crotalinae (pit vipers) Gloydius Gloydius brevicaudus (Korean slamosa snake) (Agkistrodon halys brevicaudus) |
| Enzyme Sequence | MNSLVALVLLGQIIGSTLSFQLGPNMDCNTKGTKDWADIGVRYINEHKLDGYKNALNIIKIFRLLPSDGRSVIVHFKLNLLETKCHVLDPTPVENCAVRQQHNHAVEMDCNVRIIHDIATFEDEVFVKCKSTPDSVENVRRNCPKCPILLPPNDPHVVDSVEYVLNKHNEKLSGHVYEVLEISRGQHKYEPEAFYVEFAIVEVNCTAQEARDGHHQCHPYTAGEDHIAFCRATVFRSHASLEKPKDENFESDCVILDVKEGHAHSHLIQQHIEKYSTSPGHNSTDEYVVECPVAFVEKEVPTDMSDHDTPPVKGCPGRVLHFQL |
| Enzyme Length | 324 |
| Uniprot Accession Number | Q5KQS3 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Potent inhibitor of hemorrhagic activity but also proteolytic activities. Inhibition occurs by formation of a non-covalent complex between this protein and the proteinases at their metalloproteinase domains (By similarity). {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Disulfide bond (6); Domain (2); Glycosylation (2); Signal peptide (1); Site (1) |
| Keywords | Disulfide bond;Glycoprotein;Metalloenzyme inhibitor;Metalloprotease inhibitor;Protease inhibitor;Repeat;Secreted;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..19; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 36,585 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |