| IED ID | IndEnz0002006388 |
| Enzyme Type ID | protease006388 |
| Protein Name |
Hepatocyte growth factor-like protein Macrophage stimulatory protein Macrophage-stimulating protein MSP Cleaved into: Hepatocyte growth factor-like protein alpha chain; Hepatocyte growth factor-like protein beta chain |
| Gene Name | MST1 HGFL |
| Organism | Bos taurus (Bovine) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Laurasiatheria Artiodactyla Ruminantia Pecora Bovidae Bovinae Bos (oxen cattle) Bos taurus (Bovine) |
| Enzyme Sequence | MGWLPLLLLLIWFSGAPGQRSPLNDFQVLRGTELQHLLHSVGPGPWQEDVANAEECAGLCGPLLDCRAFHYNLSSHGCQLLPWTQHSPHTRLQRSGRCDLFQKKNYVRTCIVDNGVEYRGTVAITVGGLPCQRWSHRFPNDHKFTPTLRNGLEENFCRNPDRDPGGPWCYTTDPAVRFQSCGIKSCREATCLWCNGEDYRGSVDSTESGRECQRWDLQHPHPHPFEPGFWTKIWTTTIAGIRTARSGPGAIPPTRRWRESSATYPAAVQRSEAQPSQEATTLNCFRGKGEGYRGTVNTTAAGVPCQRWDAQLPHQHRFAPEKYACKDLRENFCRNPDGSEAPWCFTSRPGMRMAFCYQIRRCTDDVRPEDCYHGAGELYRGSVSKTRKGIRCQNWSAETPHKPQFKHTSAPHTPLEENFCRNPDGDSHGPWCYTTDPGTPFDYCALRRCDDDQQPSILETAHQVLFDKCGKRVTRVDPLHSKLRVVGGQPGNSPWTVSLRNRQGQHFCGGSLVKEQWVLTARQCFSSCHMSLVGYEVWLGTLFQDPQPGEPDLQHIPMAKMVCGPSGSQLVLLKLERPVILNQRVALICLPPERYVVPPGTRCEIAGWGETKGTGDDTVLNIALLSVISNQECNVKHRGRVRESEMCTAGLLAPVGACEGDYGGPLACFTHDCWVLQGIIIPNRVCARPRWPAVFMRVSVFVDWIHKVMRLG |
| Enzyme Length | 712 |
| Uniprot Accession Number | Q24K22 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (3); Disulfide bond (16); Domain (6); Glycosylation (3); Signal peptide (1) |
| Keywords | Disulfide bond;Glycoprotein;Kringle;Reference proteome;Repeat;Secreted;Serine protease homolog;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | PTM: Cleaved after Arg-484, probably by HPN/Hepsin, to yield the active form consisting of two disulfide-linked chains. {ECO:0000250}. |
| Signal Peptide | SIGNAL 1..18; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 79,973 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |