| IED ID | IndEnz0002006451 |
| Enzyme Type ID | protease006451 |
| Protein Name |
Extracellular metalloproteinase MEP EC 3.4.24.- Elastinolytic metalloproteinase MEP Fungalysin MEP |
| Gene Name | MEP Lema_P068070.1 |
| Organism | Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta dothideomyceta Dothideomycetes Pleosporomycetidae Pleosporales Pleosporineae Leptosphaeriaceae Leptosphaeria Leptosphaeria maculans species complex Leptosphaeria maculans (Blackleg fungus) (Phoma lingam) Leptosphaeria maculans 'brassicae' group Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8) (Blackleg fungus) (Phoma lingam) |
| Enzyme Sequence | MRAFLLASLASLPAVNVYAHPTHNSRGLTRRAVDLDAFRPKVPTSYTNATAVQADPEIPTLARRADPEQVASELVAKILPDAQFRLVSDHYVGTNGVAHFYYKQTVHGLDVDSGDFNVNIGKDGNVFSFGNSFYKGKLPAAPTLKRDTEAAANALRSAVNVLSLPMSAESATAVPKEGSDAFTITQTSGAVKEPEARLVYVQDASGNLKLAWRVETDIQSNWLLTYVDAEDGSQVHAVVDYAAEATYEVYPWGISDPTEGERVVLTDPFDRQASEFGWHSDGTTEFNTTRGNNGLAHTNWENLSSGYLNFPRPSSADLKFEYPYSLEETDYKAYANASITQLYYTSNAYHDLLHTLGFNERAGNFEINNNGAGGRGGDLVYLNTQDGGGVNNANFLTPPDGQPPRMRMFIWTKTSPSRDSSFDAGVVIHEYTHGLSSRLTGGPANAGCLSSIESGGMGEGWSDFYATAIRLKPADTRATDYPMGAWIEGDSRGIRNFLYSTSMETNPQVYTNVDQYIRVHPIGNIWASMLYEVLWNLIDKHGKNDAAKPDFDANGVPTDGKYLTMKLVLDGMALQPCNPTFVSARDAIIDADKALTGGSNACEIWRGFAKRGLGAGARYDPTTRTDSFELPEGVC |
| Enzyme Length | 635 |
| Uniprot Accession Number | E4ZJL4 |
| Absorption | |
| Active Site | ACT_SITE 430; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.24.- |
| Enzyme Function | FUNCTION: Secreted metalloproteinase that allows assimilation of proteinaceous substrates. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (1); Chain (1); Glycosylation (3); Metal binding (2); Propeptide (1); Signal peptide (1) |
| Keywords | Glycoprotein;Hydrolase;Metal-binding;Metalloprotease;Protease;Reference proteome;Secreted;Signal;Zinc;Zymogen |
| Interact With | |
| Induction | INDUCTION: Expression is controlled by the prtT transcription factor. |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..19; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 69,222 |
| Kinetics | |
| Metal Binding | METAL 429; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095; METAL 433; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095 |
| Rhea ID | |
| Cross Reference Brenda |