Detail Information for IndEnz0002006584
IED ID IndEnz0002006584
Enzyme Type ID protease006584
Protein Name Adapter protein MecA
Gene Name mecA BpOF4_01905
Organism Alkalihalobacillus pseudofirmus (strain ATCC BAA-2126 / JCM 17055 / OF4) (Bacillus pseudofirmus)
Taxonomic Lineage cellular organisms Bacteria Terrabacteria group Firmicutes Bacilli Bacillales Bacillaceae Alkalihalobacillus Alkalihalobacillus pseudofirmus (Bacillus pseudofirmus) Alkalihalobacillus pseudofirmus (strain ATCC BAA-2126 / JCM 17055 / OF4) (Bacillus pseudofirmus)
Enzyme Sequence MDIERVNDTTIKFFITYKDIEDRGFDRDEIWYNRERGEELFFEMMNEANDRDEFELDGPLWIQVHALDKGLEIVVTRGQVSDGNVKLEIPVSQDKENTDENIVDLMTGHSSEDDEGIDTDQLEIVIGFNDFEDIISLSHNFFIDDLENELYHFEGRYYLHVLFNDDQYNEDEQDDMLSQMLEYGYETDLSIHRMQEYGKEIIGEYALKHLRGHFPQN
Enzyme Length 217
Uniprot Accession Number O66042
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC. {ECO:0000255|HAMAP-Rule:MF_01124}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1)
Keywords Competence;Reference proteome;Sporulation
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 25,758
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda