| IED ID |
IndEnz0002006606 |
| Enzyme Type ID |
protease006606 |
| Protein Name |
Panulirin
|
| Gene Name |
|
| Organism |
Panulirus argus (Caribbean spiny lobster) (Palinurus argus) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Metazoa
Eumetazoa
Bilateria
Protostomia
Ecdysozoa
Panarthropoda
Arthropoda
Mandibulata
Pancrustacea
Crustacea
Multicrustacea
Malacostraca
Eumalacostraca
Eucarida
Decapoda
Pleocyemata
Achelata
Palinuroidea
Palinuridae (spiny lobsters)
Panulirus
Panulirus argus (Caribbean spiny lobster) (Palinurus argus)
|
| Enzyme Sequence |
MKNKAVLMLMALFLVAVTQVHGDPEPSYKARSCTAYGYFCMIPPRCRGTVVANHWCRARGHICCSSPSNVYGKNQLLAA |
| Enzyme Length |
79 |
| Uniprot Accession Number |
B3EWX6 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: Involved in the melanization cascade in response to lipopolysaccharide (LPS). In vitro, reversibly and competitively inhibits trypsin (Ki=8.6 nM) but not serine proteases chymotrypsin, elastase, subtilisin, thrombin and plasmin, cysteine peptidase papain or metallopeptidase carboxypeptidase A. {ECO:0000269|PubMed:24047891}. |
| Temperature Dependency |
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| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Disulfide bond (3); Peptide (1); Propeptide (2); Sequence conflict (1); Signal peptide (1) |
| Keywords |
Direct protein sequencing;Disulfide bond;Immunity;Protease inhibitor;Serine protease inhibitor;Signal |
| Interact With |
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| Induction |
|
| Subcellular Location |
|
| Modified Residue |
|
| Post Translational Modification |
PTM: Contains 3 disulfide bonds. {ECO:0000269|PubMed:24047891}. |
| Signal Peptide |
SIGNAL 1..22; /evidence=ECO:0000255 |
| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
|
| Gene Encoded By |
|
| Mass |
8,705 |
| Kinetics |
|
| Metal Binding |
|
| Rhea ID |
|
| Cross Reference Brenda |
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