| IED ID | IndEnz0002006618 |
| Enzyme Type ID | protease006618 |
| Protein Name |
Phosphatidylcholine transfer protein PC-TP START domain-containing protein 2 StARD2 StAR-related lipid transfer protein 2 |
| Gene Name | PCTP STARD2 |
| Organism | Bos taurus (Bovine) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Laurasiatheria Artiodactyla Ruminantia Pecora Bovidae Bovinae Bos (oxen cattle) Bos taurus (Bovine) |
| Enzyme Sequence | MDPGAGAFSEEQFREACAELQRPALSGAAWELLVETQGISVYRLLDQQTGLYAYKVFGVLEDCLPDLLADVYMDLAYRKQWDQYVKELYEKECSGETVVYWQVKYPFPMSNRDYVYVRQRQELDFEGQKVHVILAQSTSEPQFPEKSGVIRVKHYKQRLAIQSDGKRGSKVFMYYFDNPGGQIPSWVINWAAKNGVPNFLKDMVKACQNYKKT |
| Enzyme Length | 213 |
| Uniprot Accession Number | P02720 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | BINDING 72; /note=Phosphatidylcholine; /evidence=ECO:0000250; BINDING 78; /note=Phosphatidylcholine; /evidence=ECO:0000250; BINDING 157; /note=Phosphatidylcholine; /evidence=ECO:0000250 |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Catalyzes the transfer of phosphatidylcholine between membranes. Binds phosphatidylcholine in a tight 1:1 stoichiometric complex. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Binding site (3); Chain (1); Domain (1); Modified residue (2); Mutagenesis (1); Region (1); Sequence conflict (1) |
| Keywords | Acetylation;Cytoplasm;Direct protein sequencing;Lipid transport;Lipid-binding;Phosphoprotein;Reference proteome;Transport |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cytoplasm. |
| Modified Residue | MOD_RES 1; /note=N-acetylmethionine; /evidence=ECO:0000269|PubMed:7042332; MOD_RES 139; /note=Phosphoserine; /evidence=ECO:0000250|UniProtKB:Q9UKL6 |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 24,643 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |