| IED ID | IndEnz0002006697 |
| Enzyme Type ID | protease006697 |
| Protein Name |
Calpain-like protease palB/RIM13 EC 3.4.22.- Cysteine protease RIM13 |
| Gene Name | RIM13 KLLA0F07183g |
| Organism | Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Saccharomycotina (true yeasts) Saccharomycetes Saccharomycetales Saccharomycetaceae Kluyveromyces Kluyveromyces lactis (Yeast) (Candida sphaerica) Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) |
| Enzyme Sequence | MPRGAQAMLEKQADSVWNQLYEICWNFYVKNVWDINTFKAIVDKIEKSDDKQLIRFLIWFNDARKRSNFNDKFQWMTSFLYGRRYPPLGDDLVVKEPWNDLQQLDSIIKYGNEPIDLVKMQPDFTTEERIVQNRRVNNCSLICSLTNAREENQIKSYSVHNVFNVILHFNGSNRLVSVLRDSNFPKCSKDGAALTLFSHNIEDMLIELAYFEIKNNRNYAYGGSNTATDTYLLTGWIPEILNLGDVSFSEIRKCYQFNAMLALGTDSVKGKEVTENHDFVVTSVNWKKEQFTILNPHGTENPTVYTWDDLIKEFKWLYVNWDPYSKYTQRVKLHDRYPDKFNAYPTWTQKPLMCIENKSNSIQNCHLYLERHLLDDSILESNLTIGEIPRSGFTAVSAEGNNSGFCNMQLRLNPHETRLIFYHSDKKCNLTFHLLSNSGLVSMSKCKSDILTAESSWNITNNQWTIGTSEYFKSPVFKLKSDGFDDTYLDFELVSQLPAKVNFQIFESDDYALQRPIFKNDTYSPQIFSKHGVRLLKGREYFIVCSIAHHITSPFIFTLRNPETKQSKFELSPYSLGFGGLRYNEVLRCKTRITISVSNFTRLFVLLFTSASKTNGRLTLRLYEKETEEILFEQIETRYDLSVKPFPIPNIELKPASYVLEIFYNADVVICNLGTSHRAIFESDL |
| Enzyme Length | 685 |
| Uniprot Accession Number | Q6CKY3 |
| Absorption | |
| Active Site | ACT_SITE 139; /evidence=ECO:0000250; ACT_SITE 277; /evidence=ECO:0000250; ACT_SITE 295; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.22.- |
| Enzyme Function | FUNCTION: Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Domain (1) |
| Keywords | Hydrolase;Protease;Reference proteome;Thiol protease |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 79,686 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |