| IED ID | IndEnz0002006743 |
| Enzyme Type ID | protease006743 |
| Protein Name |
Prohead protease GP4 |
| Gene Name | 4 |
| Organism | Enterobacteria phage HK97 (Bacteriophage HK97) |
| Taxonomic Lineage | Viruses Duplodnaviria Heunggongvirae Uroviricota Caudoviricetes Caudovirales Siphoviridae (phages with long non-contractile tails) Hendrixvirinae Byrnievirus Enterobacteria phage HK97 (Bacteriophage HK97) |
| Enzyme Sequence | MPEIVKTLSFDETEIKFTGDGKQGIFEGYASVFNNTDSDGDIILPGAFKNALANQTRKVAMFFNHKTWELPVGKWDSLAEDEKGLYVRGQLTPGHSGAADLKAAMQHGTVEGMSVGFSVAKDDYTIIPTGRIFKNIQALREISVCTFPANEQAGIAAMKSVDGIETIRDVENWLRDSVGLTKSQAVGLIARFKSAIRSESEGDGNEAQINALLQSIKSFPSNLGK |
| Enzyme Length | 225 |
| Uniprot Accession Number | P49860 |
| Absorption | |
| Active Site | ACT_SITE 65; /evidence=ECO:0000250|UniProtKB:Q6QGD7; ACT_SITE 114; /evidence=ECO:0000250|UniProtKB:Q6QGD7; ACT_SITE 141; /evidence=ECO:0000250|UniProtKB:Q6QGD7 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Protease involved in virion assembly and maturation. {ECO:0000250|UniProtKB:Q6QGD7}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1) |
| Keywords | Hydrolase;Late protein;Protease;Viral capsid assembly;Viral capsid maturation;Viral release from host cell;Virion |
| Interact With | P49861 |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Virion {ECO:0000250|UniProtKB:Q6QGD7}. Note=Present in the capsid. {ECO:0000250|UniProtKB:Q6QGD7}. |
| Modified Residue | |
| Post Translational Modification | PTM: Cleaves itself autocatalytically to yield the mature form of the protease. {ECO:0000250|UniProtKB:Q6QGD7}. |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 24,392 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |