| IED ID |
IndEnz0002006760 |
| Enzyme Type ID |
protease006760 |
| Protein Name |
Cystatin J
|
| Gene Name |
|
| Organism |
Cyanea capillata (Lion's mane jellyfish) (Cyanea arctica) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Metazoa
Eumetazoa
Cnidaria
Scyphozoa (jellyfishes)
Semaeostomeae
Cyaneidae
Cyanea
Cyanea capillata (Lion's mane jellyfish) (Cyanea arctica)
|
| Enzyme Sequence |
MHLYLCVLVCLSIGMANCLLPGGIRRMTDEEIQNDEILLTGVEFAVDKYNSDTNSRLIATNVISATVQVVAGFKYNALIELRPRLCVQDPKTKIATCPLRMNLPTKCSFTFLYQSWVPQKYSMLSTKCLRA |
| Enzyme Length |
131 |
| Uniprot Accession Number |
Q331K1 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: This recombinant protein inhibits the C1 cysteine protease papain (Ki is below 0.5 nM). {ECO:0000269|PubMed:14644559}. |
| Temperature Dependency |
|
| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Chain (1); Disulfide bond (2); Domain (1); Motif (1); Signal peptide (1); Site (1) |
| Keywords |
Disulfide bond;Nematocyst;Protease inhibitor;Secreted;Signal;Thiol protease inhibitor |
| Interact With |
|
| Induction |
|
| Subcellular Location |
SUBCELLULAR LOCATION: Secreted. Nematocyst {ECO:0000250}. |
| Modified Residue |
|
| Post Translational Modification |
|
| Signal Peptide |
SIGNAL 1..18; /evidence=ECO:0000255 |
| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
MOTIF 68..72; /note=Secondary area of contact; /evidence=ECO:0000250 |
| Gene Encoded By |
|
| Mass |
14,739 |
| Kinetics |
|
| Metal Binding |
|
| Rhea ID |
|
| Cross Reference Brenda |
|