| IED ID | IndEnz0002006894 |
| Enzyme Type ID | protease006894 |
| Protein Name |
Collagenolytic protease 23 kDa EC 3.4.24.7 Fragment |
| Gene Name | |
| Organism | Chionoecetes opilio (Crab-beetle) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Panarthropoda Arthropoda Mandibulata Pancrustacea Crustacea Multicrustacea Malacostraca Eumalacostraca Eucarida Decapoda Pleocyemata Brachyura (short-tailed crabs) Eubrachyura Heterotremata Majoidea Majidae (spider crabs) Chionoecetes Chionoecetes opilio (Crab-beetle) |
| Enzyme Sequence | AAILQDEYLXSGGVVPYVFG |
| Enzyme Length | 20 |
| Uniprot Accession Number | P34156 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Cleavage of the triple helix of collagen at about three-quarters of the length of the molecule from the N-terminus, at 775-Gly-|-Ile-776 in the alpha-1(I) chain. Cleaves synthetic substrates and alpha-macroglobulins at bonds where P1' is a hydrophobic residue.; EC=3.4.24.7; |
| DNA Binding | |
| EC Number | 3.4.24.7 |
| Enzyme Function | FUNCTION: This enzyme is a metal protease capable of degrading the native triple helix of collagen. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Domain (1); Non-terminal residue (1) |
| Keywords | Collagen degradation;Direct protein sequencing;Hydrolase;Metalloprotease;Protease;Zinc |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 2,110 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |