Detail Information for IndEnz0002006941
IED ID IndEnz0002006941
Enzyme Type ID protease006941
Protein Name F-box/SPRY domain-containing protein 1
F-box synaptic protein 1
Gene Name Bm1_56115
Organism Brugia malayi (Filarial nematode worm)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Nematoda (roundworms) Chromadorea Rhabditida Spirurina Spiruromorpha Filarioidea Onchocercidae Brugia Brugia malayi (Filarial nematode worm)
Enzyme Sequence MFTEGDKFNQTVVETDLEQAVDVACRNAQDCCHSKSFTCFTRRMRAVSAARLPHVVLLAVFEYLNLKDLARCMRVCKHWLTVLQYPDSFVWRRLARTVIPDEALNDFSLLSEIPSFKDKLRAFCYAWNPNDSSKNNYLRPNGFTVHRNPVAQSTDSVRGKIGVNSGIHAWEFTWEGPLGTVACIGLATKHAALHCQGYVALLGSDDQSWGWNLVDNQLLHNSKPISPYPHINNPPKYQMGERIRMIVDCEQHSMYFEKGSEFLGIAFSRLPPLKLFPAMCAVYGNTEVSMVYIGPPLLG
Enzyme Length 299
Uniprot Accession Number A8QGZ7
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which may regulate restriction and/or maturation of synapses. {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway PATHWAY: Protein modification; protein ubiquitination.
nucleotide Binding
Features Chain (1); Domain (2)
Keywords Cell junction;Reference proteome;Synapse;Ubl conjugation pathway
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Cell junction, synapse {ECO:0000250}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 33,808
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda