| IED ID |
IndEnz0002006995 |
| Enzyme Type ID |
protease006995 |
| Protein Name |
Protein DA1-related 1
|
| Gene Name |
DAR1 At4g36860 AP22.33 C7A10.500 |
| Organism |
Arabidopsis thaliana (Mouse-ear cress) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Viridiplantae
Streptophyta
Streptophytina
Embryophyta
Tracheophyta
Euphyllophyta
Spermatophyta
Magnoliopsida
Mesangiospermae
eudicotyledons
Gunneridae
Pentapetalae
rosids
malvids
Brassicales
Brassicaceae
Camelineae
Arabidopsis
Arabidopsis thaliana (Mouse-ear cress)
|
| Enzyme Sequence |
MGWLTKILKGSSHKFSDGQCNGRYREDRNLEGPRYSAEGSDFDKEEIECAIALSLSEQEHVIPQDDKGKKIIEYKSETEEDDDDDEDEDEEYMRAQLEAAEEEERRVAQAQIEEEEKRRAEAQLEETEKLLAKARLEEEEMRRSKAQLEEDELLAKALQESMNVGSPPRYDPGNILQPYPFLIPSSHRICVGCQAEIGHGRFLSCMGGVWHPECFCCNACDKPIIDYEFSMSGNRPYHKLCYKEQHHPKCDVCHNFIPTNPAGLIEYRAHPFWMQKYCPSHERDGTPRCCSCERMEPKDTKYLILDDGRKLCLECLDSAIMDTHECQPLYLEIREFYEGLHMKVEQQIPMLLVERSALNEAMEGEKHGHHHLPETRGLCLSEEQTVTTVLRRPRIGAGYKLIDMITEPCRLIRRCEVTAILILYGLPRLLTGSILAHEMMHAWLRLNGYPNLRPEVEEGICQVLAHMWLESETYAGSTLVDIASSSSSAVVSASSKKGERSDFEKKLGEFFKHQIESDSSSAYGDGFRQGNQAVLKHGLRRTLDHIRLTGTFP |
| Enzyme Length |
553 |
| Uniprot Accession Number |
Q8W4F0 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: Acts redundantly with DA1 and DAR2 to regulate endoreduplication during leaf development. Together with DA1 and DAR2, modulates the protein stability of the transcription factors TCP14 and TCP15, which repress endoreduplication by directly regulating the expression of cell-cycle genes. {ECO:0000269|PubMed:25757472}. |
| Temperature Dependency |
|
| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Chain (1); Compositional bias (3); Domain (5); Erroneous gene model prediction (2); Frameshift (2); Modified residue (1); Region (2); Sequence conflict (2) |
| Keywords |
LIM domain;Metal-binding;Phosphoprotein;Reference proteome;Repeat;Ubl conjugation;Zinc |
| Interact With |
|
| Induction |
|
| Subcellular Location |
|
| Modified Residue |
MOD_RES 166; /note=Phosphoserine; /evidence=ECO:0007744|PubMed:19245862 |
| Post Translational Modification |
PTM: Polyubiquitinated by DA2. {ECO:0000269|PubMed:28167503}. |
| Signal Peptide |
|
| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
17317660;
20226671;
21798944;
32209225;
|
| Motif |
|
| Gene Encoded By |
|
| Mass |
63,308 |
| Kinetics |
|
| Metal Binding |
|
| Rhea ID |
|
| Cross Reference Brenda |
|