| IED ID | IndEnz0002007089 |
| Enzyme Type ID | protease007089 |
| Protein Name |
Chymotrypsin B EC 3.4.21.1 Cleaved into: Chymotrypsin B chain A; Chymotrypsin B chain B |
| Gene Name | |
| Organism | Gadus morhua (Atlantic cod) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Actinopterygii Actinopteri Neopterygii Teleostei Osteoglossocephalai Clupeocephala Euteleosteomorpha Neoteleostei Eurypterygia Ctenosquamata Acanthomorphata Paracanthopterygii Zeiogadaria Gadariae Gadiformes (cods and others) Gadoidei Gadidae (cods) Gadus Gadus morhua (Atlantic cod) |
| Enzyme Sequence | CGSPAIQPQVTGYARIVNGEEAVPHSWPWQVSLQQSNGFHFCGGSLINENWVVTAAHCNVRTYHRVIVGEHDKASDENIQILKPSMVFTHPKWDSRTINNDISLIKLASPAVLGTNVSPVCLGESSDVFAPGMKCVTSGWGLTRYNAPGTPNKLQQAALPLMSNEECSQTWGNNMISDVMICAGAAGATSCMGDSGGPLVCQKDNVWTLVGIVSWGSSRCSVTTPAVYARVTELRGWVDQILAAN |
| Enzyme Length | 245 |
| Uniprot Accession Number | P80646 |
| Absorption | |
| Active Site | ACT_SITE 57; /note=Charge relay system; /evidence=ECO:0000250; ACT_SITE 101; /note=Charge relay system; /evidence=ECO:0000250; ACT_SITE 195; /note=Charge relay system; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Preferential cleavage: Tyr-|-Xaa, Trp-|-Xaa, Phe-|-Xaa, Leu-|-Xaa.; EC=3.4.21.1; Evidence={ECO:0000255|PROSITE-ProRule:PRU10078, ECO:0000255|PROSITE-ProRule:PRU10079}; |
| DNA Binding | |
| EC Number | 3.4.21.1 |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (2); Disulfide bond (5); Domain (1); Propeptide (1); Sequence conflict (3) |
| Keywords | Digestion;Direct protein sequencing;Disulfide bond;Hydrolase;Protease;Secreted;Serine protease;Zymogen |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted, extracellular space. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 26,260 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |