| IED ID | IndEnz0002007099 |
| Enzyme Type ID | protease007099 |
| Protein Name |
Probable aspartic-type endopeptidase CTSD EC 3.4.23.- Fragment |
| Gene Name | CTSD MCYG_01216 |
| Organism | Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Onygenales Arthrodermataceae (dermatophytes) Microsporum Arthroderma otae (Microsporum canis) Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis) |
| Enzyme Sequence | SLIDTGASRTWVFGSDCTSKSCGAHNTFGKEDSKTIKVTDEKWDVAYGTGKVAGVIVNDTMSFAGFELDTPFGSATTASDDFMSYPMDGILGIGPQDSKAKVPTVIQLLMQQKLLKSNIIGINLQRNSDGATDGQITFGDVDKSKFSGELAYSNVVSGGYQWEIAVDDIIVDGKPLNFQGRSGIVDTGTSFLLLPPDDADLIHSKIPKSAKSSVFYTVPCSTTTNIELSISGVKYAIKPKDYVGYESTTKGICNSLIIGRQAIGPKQWLLGDVFLKNVYSVYDFDKNRVGLAARKYGETKDPPSSSHPPPAPTSNKASGGSPGLPEQSGTSSATTSTTGEPSSGSTASPSAASSVSMSAWLSLAVFLSTASSLILWD |
| Enzyme Length | 377 |
| Uniprot Accession Number | C5FEK4 |
| Absorption | |
| Active Site | ACT_SITE 4; /evidence=ECO:0000255|PROSITE-ProRule:PRU10094; ACT_SITE 186; /evidence=ECO:0000255|PROSITE-ProRule:PRU10094 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.23.- |
| Enzyme Function | FUNCTION: Secreted aspartic-type endopeptidase which is secreted and contributes to virulence. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Chain (1); Compositional bias (1); Domain (1); Erroneous initiation (1); Glycosylation (1); Lipidation (1); Non-terminal residue (1); Propeptide (1); Region (1) |
| Keywords | Aspartyl protease;Cell membrane;GPI-anchor;Glycoprotein;Hydrolase;Lipoprotein;Membrane;Protease;Reference proteome;Virulence |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor, GPI-anchor {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 39,731 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |