| IED ID | IndEnz0002007159 |
| Enzyme Type ID | protease007159 |
| Protein Name |
Metacaspase-1 EC 3.4.22.- |
| Gene Name | casA BC1G_11354 |
| Organism | Botryotinia fuckeliana (strain B05.10) (Noble rot fungus) (Botrytis cinerea) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta sordariomyceta Leotiomycetes Helotiales Sclerotiniaceae Botrytis Botryotinia fuckeliana (Noble rot fungus) (Botrytis cinerea) Botryotinia fuckeliana (strain B05.10) (Noble rot fungus) (Botrytis cinerea) |
| Enzyme Sequence | MEAMEHQTSSTRPNPTTRRIKLPPLYAVLLELSLTLISPQPAYGAPPPQGGGYGYHQPPPPQQPYGYSQPPPQQYGGYNGVPPNAPQYGRPGMPSVNSNAYTNGNQNAPPPPPQGMHAFGQGAPQGYAFQYSNCTGKRKALLIGINYFGQRGQLRGCINDVKNMSSYLHENFGYQRDDMVLLTDDQQNPMSQPTKQNILRAMHWLVKDARPNDSLFFHYSGHGGQTKDLDGDEEDGYDEVIYPVDFRQVGHIVDDEMHRIMVQPLQPGVRLTAIFDSCHSGTALDLPYVYSTQGVLKEPNLAKEAGQGLLGVISSYSQGDMSGVASNLMGFFKKATTGDDAYNKTLATKTSPADVIMWSGSKDDQTSADATIAAQATGAMSWAFITAMKKNPQQSYVQLLNSIRDELATKYTQKPQLSCSHPLSMFSPLAL |
| Enzyme Length | 431 |
| Uniprot Accession Number | A6SDT7 |
| Absorption | |
| Active Site | ACT_SITE 222; /evidence=ECO:0000250; ACT_SITE 278; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.22.- |
| Enzyme Function | FUNCTION: Involved in cell death (apoptosis). {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Chain (1); Compositional bias (2); Propeptide (1); Region (1) |
| Keywords | Apoptosis;Hydrolase;Protease;Thiol protease;Zymogen |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 47,160 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |