| IED ID |
IndEnz0002007168 |
| Enzyme Type ID |
protease007168 |
| Protein Name |
Lipoprotein NlpI
|
| Gene Name |
nlpI yhbM b3163 JW3132 |
| Organism |
Escherichia coli (strain K12) |
| Taxonomic Lineage |
cellular organisms
Bacteria
Proteobacteria
Gammaproteobacteria
Enterobacterales
Enterobacteriaceae
Escherichia
Escherichia coli
Escherichia coli (strain K12)
|
| Enzyme Sequence |
MKPFLRWCFVATALTLAGCSNTSWRKSEVLAVPLQPTLQQEVILARMEQILASRALTDDERAQLLYERGVLYDSLGLRALARNDFSQALAIRPDMPEVFNYLGIYLTQAGNFDAAYEAFDSVLELDPTYNYAHLNRGIALYYGGRDKLAQDDLLAFYQDDPNDPFRSLWLYLAEQKLDEKQAKEVLKQHFEKSDKEQWGWNIVEFYLGNISEQTLMERLKADATDNTSLAEHLSETNFYLGKYYLSLGDLDSATALFKLAVANNVHNFVEHRYALLELSLLGQDQDDLAESDQQ |
| Enzyme Length |
294 |
| Uniprot Accession Number |
P0AFB1 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: May be involved in cell division. May play a role in bacterial septation or regulation of cell wall degradation during cell division. Negatively controls the production of extracellular DNA (eDNA). {ECO:0000269|PubMed:10400590, ECO:0000269|PubMed:20833130}. |
| Temperature Dependency |
|
| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Chain (1); Frameshift (1); Helix (15); Lipidation (2); Mutagenesis (4); Repeat (3); Signal peptide (1) |
| Keywords |
3D-structure;Cell cycle;Cell division;Cell membrane;Direct protein sequencing;Lipoprotein;Membrane;Palmitate;Reference proteome;Repeat;Signal;TPR repeat |
| Interact With |
|
| Induction |
INDUCTION: By L-arabinose. By high-pressure at 400MPa for 5 minutes. {ECO:0000269|PubMed:10400590, ECO:0000269|PubMed:16597971}. |
| Subcellular Location |
SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor. |
| Modified Residue |
|
| Post Translational Modification |
|
| Signal Peptide |
SIGNAL 1..18 |
| Structure 3D |
X-ray crystallography (5) |
| Cross Reference PDB |
1XNF;
5WQL;
6IQQ;
6IQS;
6IQU;
|
| Mapped Pubmed ID |
15690043;
29138488;
31387902;
|
| Motif |
|
| Gene Encoded By |
|
| Mass |
33,621 |
| Kinetics |
|
| Metal Binding |
|
| Rhea ID |
|
| Cross Reference Brenda |
|