| IED ID | IndEnz0002007213 |
| Enzyme Type ID | protease007213 |
| Protein Name |
Gag-yes polyprotein Cleaved into: Matrix protein p19; p2A; p2B; p10, truncated; V-yes oncogene |
| Gene Name | gag |
| Organism | Avian sarcoma virus (strain Y73) |
| Taxonomic Lineage | Viruses Riboviria Pararnavirae Artverviricota Revtraviricetes Ortervirales Retroviridae Orthoretrovirinae Alpharetrovirus Avian sarcoma virus (strain Y73) |
| Enzyme Sequence | MEAVIKVISSACKTYCGKTSPSKKEIGAMLSLLQKEGLLMSPSDLYSPGSWDPITAALSQRAMVLGKSGELKTWGLVLGALKAAREEQVTSEQAKFWLGLGGGRVSPPGPECIEKPATERRIDKGEEVGETTVQRDAKMAPEETATPKTVGTSCYHCGTASGCNCATATASAPPPPYVGSGLCPSLAGVGEQRKRGDDTPRGAEQPRAEPRHTGLTLGPARSARLPPPAPLPSSLPLLPPFPPRVAAVPGGAGGAPLPSLSPSFFHPRRRGRAEATVGCIKSKE |
| Enzyme Length | 284 |
| Uniprot Accession Number | P03327 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (6); Compositional bias (2); Motif (1); Region (3); Site (4) |
| Keywords | Host-virus interaction;Oncogene;Viral budding;Viral budding via the host ESCRT complexes;Viral matrix protein;Viral release from host cell;Virion |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: [Matrix protein p19]: Virion {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | PTM: Gag polyprotein: Specific enzymatic cleavages in vivo yield mature proteins. {ECO:0000250|UniProtKB:P03322}. |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | MOTIF 174..177; /note=PPXY motif; /evidence=ECO:0000250|UniProtKB:P03322 |
| Gene Encoded By | |
| Mass | 29,526 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |