Detail Information for IndEnz0002007220
IED ID IndEnz0002007220
Enzyme Type ID protease007220
Protein Name Receptor for activated C kinase 1A
Guanine nucleotide-binding protein subunit beta-like protein A
WD-40 repeat auxin-dependent protein ARCA
Gene Name RACK1A ARCA At1g18080 T10F20.9 T10O22.6
Organism Arabidopsis thaliana (Mouse-ear cress)
Taxonomic Lineage cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis Arabidopsis thaliana (Mouse-ear cress)
Enzyme Sequence MAEGLVLKGTMRAHTDMVTAIATPIDNADIIVSASRDKSIILWKLTKDDKAYGVAQRRLTGHSHFVEDVVLSSDGQFALSGSWDGELRLWDLAAGVSTRRFVGHTKDVLSVAFSLDNRQIVSASRDRTIKLWNTLGECKYTISEGGEGHRDWVSCVRFSPNTLQPTIVSASWDKTVKVWNLSNCKLRSTLAGHTGYVSTVAVSPDGSLCASGGKDGVVLLWDLAEGKKLYSLEANSVIHALCFSPNRYWLCAATEHGIKIWDLESKSIVEDLKVDLKAEAEKADNSGPAATKRKVIYCTSLNWSADGSTLFSGYTDGVIRVWGIGRY
Enzyme Length 327
Uniprot Accession Number O24456
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Major component of the RACK1 regulatory proteins that play a role in multiple signal transduction pathways. Involved in multiple hormone responses and developmental processes (PubMed:16829549, PubMed:18715992, PubMed:18947417). MAPK cascade scaffolding protein involved in the protease IV and ArgC signaling pathway but not the flg22 pathway (PubMed:25731164). {ECO:0000269|PubMed:16829549, ECO:0000269|PubMed:18715992, ECO:0000269|PubMed:18947417, ECO:0000269|PubMed:25731164}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Alternative sequence (1); Beta strand (29); Chain (1); Repeat (7); Sequence conflict (1); Turn (4)
Keywords 3D-structure;Alternative splicing;Cytoplasm;Nucleus;Reference proteome;Repeat;Ribonucleoprotein;Ribosomal protein;Transducer;WD repeat
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:22068106}. Nucleus {ECO:0000269|PubMed:22068106}. Note=Detected in the cytoplasm and nucleus when interacting with NUDT7.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D X-ray crystallography (1)
Cross Reference PDB 3DM0;
Mapped Pubmed ID 12777046; 15010618; 15632092; 15734919; 15769804; 15821981; 15955926; 16247729; 16336779; 16502469; 16520461; 16679420; 16972165; 18431481; 18650403; 19584117; 19651700; 19832940; 20118269; 20405473; 21098678; 22195043; 22951405; 23941160; 24280008; 24591271; 25489024; 25625317; 25986967; 26697044; 26941753; 28627464; 30824009; 31021701; 31143369; 31606202; 32344669; 33784940;
Motif
Gene Encoded By
Mass 35,748
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda