| IED ID |
IndEnz0002007287 |
| Enzyme Type ID |
protease007287 |
| Protein Name |
pH-response transcription factor pacC/RIM101
|
| Gene Name |
RIM101 AFR190C |
| Organism |
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Fungi
Dikarya
Ascomycota
saccharomyceta
Saccharomycotina (true yeasts)
Saccharomycetes
Saccharomycetales
Saccharomycetaceae
Eremothecium
Eremothecium gossypii (Yeast) (Ashbya gossypii)
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Eremothecium gossypii)
|
| Enzyme Sequence |
MSHINHLLNSDEAIPSTALRSCAQRSPMSSDDELVGTAGYRENQPVPGSTLPTSPSDVSTDTENDEHQRLLCQWDACGSEFSQPELLYHHLCQDHVGRKSQRNLQLNCHWGSCTTKTVKRDHITSHLRVHVPLKPFSCSTCSRKFKRPQDLKKHLKVHMEDTMKERSRAAPGSRGVRKTGVNKGSALQEKARTLPNLTVESFVSQEMQNYYPYYKSRQHLDETLSHIILPPPAALGGTLASEPPSYTRKAVSFFTTLSQDMSRRLPSLAPCNSPGPAGKMVMLPRPEQQYARVPRYPAMPELPPLVTSPGAESHALPRGHNFRPAPLIPGSMLPSLSRFSHDKSQFVARNSYSLNQKASLNEELCENELDIALENLALDDTDALRAELQTVNIIKDYLTCLLLEDVYTESFELPASVEKSHSTLRKYPQIKV |
| Enzyme Length |
432 |
| Uniprot Accession Number |
Q753Y2 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
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| Enzyme Function |
FUNCTION: Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH. At alkaline ambient pH, activates transcription of alkaline-expressed genes (including palB/RIM101 itself) and represses transcription of acid-expressed genes (By similarity). {ECO:0000250}. |
| Temperature Dependency |
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| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Chain (1); Compositional bias (1); Motif (2); Region (2); Zinc finger (3) |
| Keywords |
Activator;Cytoplasm;DNA-binding;Metal-binding;Nucleus;Reference proteome;Repeat;Repressor;Transcription;Transcription regulation;Zinc;Zinc-finger |
| Interact With |
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| Induction |
|
| Subcellular Location |
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
| Modified Residue |
|
| Post Translational Modification |
PTM: Activated by C-terminal proteolytic cleavage by signaling protease (probably RIM13) at neutral to alkaline ambient pH. {ECO:0000250}. |
| Signal Peptide |
|
| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
MOTIF 296..299; /note=YPX[LI] motif 1; /evidence=ECO:0000255; MOTIF 427..430; /note=YPX[LI] motif 2 |
| Gene Encoded By |
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| Mass |
48,344 |
| Kinetics |
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| Metal Binding |
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| Rhea ID |
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| Cross Reference Brenda |
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