| IED ID |
IndEnz0002007289 |
| Enzyme Type ID |
protease007289 |
| Protein Name |
Ornithodorin
|
| Gene Name |
|
| Organism |
Ornithodoros moubata (Soft tick) (Argasid tick) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Metazoa
Eumetazoa
Bilateria
Protostomia
Ecdysozoa
Panarthropoda
Arthropoda
Chelicerata
Arachnida
Acari
Parasitiformes
Ixodida (ticks)
Ixodoidea
Argasidae (softbacked ticks)
Ornithodoros (relapsing fever ticks)
Ornithodoros moubata (Soft tick) (Argasid tick)
|
| Enzyme Sequence |
LNVLCNNPHTADCNNDAQVDRYFREGTTCLMSPACTSEGYASQHECQQACFVGGEDHSSEMHSSCLGDPPTSCAEGTDITYYDSDSKTCKVLAASCPSGENTFESEVECQVACGAPIEG |
| Enzyme Length |
119 |
| Uniprot Accession Number |
P56409 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: Potent (Ki = 10(-12) M) and highly selective thrombin inhibitor. |
| Temperature Dependency |
|
| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Beta strand (7); Chain (1); Disulfide bond (6); Domain (2); Helix (4); Region (1); Turn (1) |
| Keywords |
3D-structure;Disulfide bond;Protease inhibitor;Repeat;Serine protease inhibitor |
| Interact With |
|
| Induction |
|
| Subcellular Location |
|
| Modified Residue |
|
| Post Translational Modification |
|
| Signal Peptide |
|
| Structure 3D |
X-ray crystallography (1) |
| Cross Reference PDB |
1TOC;
|
| Mapped Pubmed ID |
- |
| Motif |
|
| Gene Encoded By |
|
| Mass |
12,632 |
| Kinetics |
|
| Metal Binding |
|
| Rhea ID |
|
| Cross Reference Brenda |
|