| IED ID | IndEnz0002007364 |
| Enzyme Type ID | protease007364 |
| Protein Name |
Plasmepsin VI EC 3.4.23.- Plasmepsin 6 |
| Gene Name | PMVI ASP PBANKA_0409700 |
| Organism | Plasmodium berghei (strain Anka) |
| Taxonomic Lineage | cellular organisms Eukaryota Sar Alveolata Apicomplexa Aconoidasida Haemosporida (haemosporidians) Plasmodiidae Plasmodium Plasmodium (Vinckeia) Plasmodium berghei Plasmodium berghei (strain Anka) |
| Enzyme Sequence | MTNFCIKSYLFLYLSFLLFFDIITIFHVSSIRISTVLKNDKKKKNFNTSLVEENKKYLFNEIKLNNRFKNDIKGYIQNINNFHSIIESKIPNSLLYVHEDLINFHNSQFIGDIEIGNPPQSFKVVFDTGSSNFAIPSTKCVKGGCTLHNKFDAKKSRTFMSNLKNKKESIYTYVQYGTGKSILEHGYDDVYMKGLKINKQCIGLIIEESMHPFSDLPFDGIVGLGFSDPDNSFQTKYSKSLIETIKEQNLLQQNIFSFYVPKELEKSGAITFGRANSKYAIEGEKIEWFPVISMYFWEINLLGILLPDKNFEICSNKKCRAAVDTGSSLITGPSSLMQPLIENINLEKDCSNISSLPIISFVLKNVEGKTVILDFTPDDYILQENSEEDNSSQCVIGLMSLDIPPPRGPIFIFGNVFIRKYYTIFDNDHKLVGVVKSNHNF |
| Enzyme Length | 441 |
| Uniprot Accession Number | A0A509AI82 |
| Absorption | |
| Active Site | ACT_SITE 127; /evidence=ECO:0000255|PROSITE-ProRule:PRU01103; ACT_SITE 324; /evidence=ECO:0000255|PROSITE-ProRule:PRU01103 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.23.- |
| Enzyme Function | FUNCTION: During the development in the mosquito midgut, plays a role in sporozoite egress from oocysts. {ECO:0000269|PubMed:18761621}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (2); Chain (1); Domain (1); Propeptide (1); Topological domain (2); Transmembrane (1) |
| Keywords | Aspartyl protease;Hydrolase;Membrane;Protease;Reference proteome;Signal-anchor;Transmembrane;Transmembrane helix;Zymogen |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Single-pass type II membrane protein {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 50,319 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |