| IED ID | IndEnz0002007433 |
| Enzyme Type ID | protease007433 |
| Protein Name |
RNA silencing suppressor 21 kDa protein p21 |
| Gene Name | ORF8 |
| Organism | Beet yellows virus (isolate Ukraine) (BYV) (Sugar beet yellows virus) |
| Taxonomic Lineage | Viruses Riboviria Orthornavirae Kitrinoviricota Alsuviricetes Martellivirales Closteroviridae Closterovirus Beet yellows virus Beet yellows virus (isolate Ukraine) (BYV) (Sugar beet yellows virus) |
| Enzyme Sequence | MKFFLKDGETSRALSRSESLLRRVKELGTNSQQSEISECVDEFNELASFNHLLVTVEHREWMEQHPNQSSKLRVPSRIGEMLKEIRAFLKVRVVTPMHKETASDTLNAFLEEYCRITGLAREDALREKMRKVKSVVLFHHSELLKFEVTENMFSYTELLKLNLSLRVISSQILGMAI |
| Enzyme Length | 177 |
| Uniprot Accession Number | Q08545 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Acts as suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. Binds to ssRNAs and dsRNAs in vitro. Also functions as replication enhancer. {ECO:0000269|PubMed:12642093}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Helix (9); Turn (1) |
| Keywords | 3D-structure;Host cytoplasm;RNA-binding;Reference proteome;Suppressor of RNA silencing |
| Interact With | Itself |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Host cytoplasm {ECO:0000269|PubMed:12642093}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | X-ray crystallography (1) |
| Cross Reference PDB | 2CWO; |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 20,558 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |