Detail Information for IndEnz0002007496
IED ID IndEnz0002007496
Enzyme Type ID protease007496
Protein Name Elafin
Protein WAP-1
Gene Name
Organism Sus scrofa (Pig)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Laurasiatheria Artiodactyla Suina Suidae (pigs) Sus Sus scrofa (Pig)
Enzyme Sequence MRSRSFLVLVVVFLICGTLVAQAAGRIRRPKGKGTKKILALVKGQGPVRGKDQVKGQGPVKGQDLGKSQDPVKAQLPDKGQDLGKGEDSVKGQDPFKAQLPDKLQDPVKAQPAIKRLILLTKPGSCPRILIRCLMVNPPNRCLSDAQCPGLKKCCEGFCGKACMDPK
Enzyme Length 167
Uniprot Accession Number Q29125
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Neutrophil and pancreatic elastase-specific inhibitor of skin. It may prevent elastase-mediated tissue proteolysis (By similarity). {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Disulfide bond (4); Domain (1); Propeptide (1); Region (3); Repeat (14); Signal peptide (1)
Keywords Disulfide bond;Protease inhibitor;Reference proteome;Repeat;Serine protease inhibitor;Signal
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..21; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 17,923
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda