| IED ID |
IndEnz0002007512 |
| Enzyme Type ID |
protease007512 |
| Protein Name |
Chymotrypsin inhibitor SCI-II
|
| Gene Name |
|
| Organism |
Bombyx mori (Silk moth) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Metazoa
Eumetazoa
Bilateria
Protostomia
Ecdysozoa
Panarthropoda
Arthropoda
Mandibulata
Pancrustacea
Hexapoda
Insecta
Dicondylia
Pterygota (winged insects)
Neoptera
Endopterygota
Amphiesmenoptera
Lepidoptera (butterflies and moths)
Glossata
Neolepidoptera
Heteroneura
Ditrysia
Obtectomera
Bombycoidea (hawk-moths)
Bombycidae (silkworm moths)
Bombycinae
Bombyx
Bombyx mori (Silk moth)
|
| Enzyme Sequence |
DKPTTKPICEQAFGNSGPCFAYIKLYSYNQKTKKCEEFIYGGCKGNDNRFDTLAECEQKCIK |
| Enzyme Length |
62 |
| Uniprot Accession Number |
P10832 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: Inhibits chymotrypsin and thus avoids the accidental chymotrypsin-mediated activation of prophenoloxidase. This enzyme is required by the insect immune system to produce melanin which is used to engulf foreign objects.; FUNCTION: Also inhibits trypsin weakly, this may be due to the presence of a pseudo-reactive bond in positions 44-45 (Lys-Gly). |
| Temperature Dependency |
|
| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Chain (1); Disulfide bond (3); Domain (1); Site (2) |
| Keywords |
Direct protein sequencing;Disulfide bond;Protease inhibitor;Reference proteome;Serine protease inhibitor |
| Interact With |
|
| Induction |
|
| Subcellular Location |
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| Modified Residue |
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| Post Translational Modification |
|
| Signal Peptide |
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| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
|
| Gene Encoded By |
|
| Mass |
7,067 |
| Kinetics |
|
| Metal Binding |
|
| Rhea ID |
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| Cross Reference Brenda |
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