Detail Information for IndEnz0002007545
IED ID IndEnz0002007545
Enzyme Type ID protease007545
Protein Name Pregnancy-associated glycoprotein 6
ovPAG6
EC 3.4.23.-
Pregnancy-associated glycoprotein 58a
ovPAG 58a
Gene Name
Organism Ovis aries (Sheep)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Laurasiatheria Artiodactyla Ruminantia Pecora Bovidae Caprinae Ovis Ovis aries (Sheep)
Enzyme Sequence MKWLVLLGLVSISECIVKIPLRRVKTMRKTLSEKNMLNNFLKEHAYRLSQISFRGSNLTIHPLRNTKDLVYLGNITIGTPPQEFQVVSDTGSSDLWVPSDFCAIEACSLHTRFRHLQSSTFRPTNRTFSITYGCGTVKGVVVHDTVRIGDLVSTDQPFGLSTAEHVSRCTPFDGVLGLNYPSISFWSTIPIFDKLKNEGAISEPVFAFYLSKDGQEGSVVMFGGVDHRYYKGELNWVPLIPAGNWMVHMDRIYIERNVIACSAGCKAVVDTGAAFIEGPKSQVDNMQKFIGARPRGSKYYVPCSVVNTLPSIIFRINSINYPVPGRAYILKNHRGRCYTTFKENQWSPSTEIWILGDVFLRLYFSVFDRGHDRIGLARAV
Enzyme Length 380
Uniprot Accession Number P83493
Absorption
Active Site ACT_SITE 89; /evidence=ECO:0000255|PROSITE-ProRule:PRU10094; ACT_SITE 270; /evidence=ECO:0000255|PROSITE-ProRule:PRU10094
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.23.-
Enzyme Function
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (2); Chain (1); Disulfide bond (3); Domain (1); Glycosylation (3); Propeptide (1); Signal peptide (1)
Keywords Aspartyl protease;Direct protein sequencing;Disulfide bond;Glycoprotein;Hydrolase;Protease;Reference proteome;Secreted;Signal
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted, extracellular space {ECO:0000269|PubMed:9408244}.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..15; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 42,778
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda