| IED ID | IndEnz0002007637 |
| Enzyme Type ID | protease007637 |
| Protein Name |
Collagen and calcium-binding EGF domain-containing protein 1 Full of fluid protein homolog |
| Gene Name | Ccbe1 Kiaa1983 |
| Organism | Mus musculus (Mouse) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Euarchontoglires Glires (Rodents and rabbits) Rodentia Myomorpha (mice and others) Muroidea Muridae Murinae Mus Mus Mus musculus (Mouse) |
| Enzyme Sequence | MVPPPLPSRGGAAKRQLGKSLGPLLLLLALGHTWTYREEPEDRDREVCSENKITTTKYPCLKSSGELTTCFRKKCCKGYKFVLGQCIPEDYDICAQAPCEQQCTDNFGRVLCTCYPGYRYDRERHQKRERPYCLDIDECATSNTTLCAHICINTMGSYHCECREGYILEDDGRTCTRGDKYPNDTGHEEKSENEVKAGTCCATCKEFSQMKQTVLQLKQKMALLPNNAAELGKYVNGDKVLASNAYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRHGSKGERGAPGPPGSPGPPGSFDFLLLVLADIRNDIAELQEKVFGHRTHSSAEDFPLPQEFSSYPETLDFGSGDDYSRRTEARDPEAPRNFYP |
| Enzyme Length | 408 |
| Uniprot Accession Number | Q3MI99 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Required for lymphangioblast budding and angiogenic sprouting from venous endothelium during embryogenesis. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Compositional bias (2); Disulfide bond (3); Domain (3); Erroneous initiation (1); Glycosylation (2); Region (2); Sequence conflict (3); Signal peptide (1) |
| Keywords | Angiogenesis;Calcium;Collagen;Developmental protein;Disulfide bond;EGF-like domain;Glycoprotein;Reference proteome;Repeat;Secreted;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..35; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 11217851; 12466851; 20562862; 21778431; 22252499; 23299940; 23426945; 24276893; 24552833; 24733830; 25814692; 27159393; 28687807; 28850031; 28890073; 30204931; 30281646; 31672914; 31702554; |
| Motif | |
| Gene Encoded By | |
| Mass | 44,357 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |