| IED ID | IndEnz0002007645 |
| Enzyme Type ID | protease007645 |
| Protein Name |
Probable membrane metalloprotease ARASP2, chloroplastic EC 3.4.24.- |
| Gene Name | ARASP2 At1g05140 YUP8H12.25 |
| Organism | Arabidopsis thaliana (Mouse-ear cress) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis Arabidopsis thaliana (Mouse-ear cress) |
| Enzyme Sequence | MLLNISSSPISHRIPHFLSDFNNPTSNFPPKSKTHLPKSNLSTLSNHSLYGTKNRAFYKNKRNPYNRTQALGRFDFGSLESVLEASAVLTAIIVVHETGHFLAASLQGIRVSKFAIGFGPILAKFNSNNVEYSLRAFPLGGFVGFPDNDPDSDIPVDDRNLLKNRPILDRVIVVSAGIVANVIFAYAIIFTQVVSVGLPVQESFPGVLVPDVKSFSAASRDGLLPGDVILAVDGTELSNSGSDSVSKVVDVVKRNPEHNVLLRIERGKESFEIRITPDKSFDGTGKIGVQLSPNVRFGKVRPKNIPETFSFAGREFFGLSYNVLDSLKQTFLNFSQTASKVAGPVAIIAVGAEVARSNADGLYQFAALLNLNLAVINLLPLPALDGGTLALILLEAVRGGRKLPLEVEQGIMSSGIMLVLFLGLFLIVKDTLNLDFIKEML |
| Enzyme Length | 441 |
| Uniprot Accession Number | O23053 |
| Absorption | |
| Active Site | ACT_SITE 97; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.24.- |
| Enzyme Function | FUNCTION: Metalloprotease essential for chloroplast and plant development. May be involved in regulated intramembrane proteolysis (RIP). {ECO:0000250|UniProtKB:O80885}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (1); Chain (1); Domain (1); Metal binding (2); Sequence conflict (1); Transit peptide (1); Transmembrane (3) |
| Keywords | Chloroplast;Hydrolase;Membrane;Metal-binding;Metalloprotease;Plastid;Plastid inner membrane;Protease;Reference proteome;Transit peptide;Transmembrane;Transmembrane helix;Zinc |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Plastid, chloroplast inner membrane {ECO:0000255}; Multi-pass membrane protein {ECO:0000255}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 10891285; 14576160; 18431481; 20736450; 27138552; 28441590; |
| Motif | |
| Gene Encoded By | |
| Mass | 47,775 |
| Kinetics | |
| Metal Binding | METAL 96; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095; METAL 100; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095 |
| Rhea ID | |
| Cross Reference Brenda |