| IED ID | IndEnz0002007714 |
| Enzyme Type ID | protease007714 |
| Protein Name |
Cathepsin L1 EC 3.4.22.15 Fragment |
| Gene Name | |
| Organism | Fasciola hepatica (Liver fluke) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Spiralia Lophotrochozoa Platyhelminthes Trematoda Digenea (flukes) Plagiorchiida Echinostomata Echinostomatoidea Fasciolidae Fasciola Fasciola hepatica (Liver fluke) |
| Enzyme Sequence | AVPDKIDPRESGYVTGVKDQ |
| Enzyme Length | 20 |
| Uniprot Accession Number | Q09093 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Specificity close to that of papain. As compared to cathepsin B, cathepsin L exhibits higher activity toward protein substrates, but has little activity on Z-Arg-Arg-NHMec, and no peptidyl-dipeptidase activity.; EC=3.4.22.15; |
| DNA Binding | |
| EC Number | 3.4.22.15 |
| Enzyme Function | FUNCTION: Thiol protease that assists the parasite in burrowing through the gut wall and liver of its mammalian host. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Non-terminal residue (1); Region (1) |
| Keywords | Direct protein sequencing;Disulfide bond;Hydrolase;Lysosome;Protease;Thiol protease |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Lysosome. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 2,174 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |