Detail Information for IndEnz0002007724
IED ID IndEnz0002007724
Enzyme Type ID protease007724
Protein Name Zinc carboxypeptidase
EC 3.4.17.-
Fragment
Gene Name
Organism Simulium vittatum (Striped black fly)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Panarthropoda Arthropoda Mandibulata Pancrustacea Hexapoda Insecta Dicondylia Pterygota (winged insects) Neoptera Endopterygota Diptera Nematocera Culicomorpha Chironomoidea Simuliidae (black flies) Simuliinae Simuliini Simulium Psilozia Simulium vittatum (Striped black fly)
Enzyme Sequence QYHTLPEIYSWLDRLVQEHPEHVEPVVGGKSYEGREIRGVKVSYKKGNPVVMVESNIHAREWITAATTTYLLNELLTSKNSTIREMAENYDWYIFPVTNPDGYVYTHTTDRMWRKTRSPNPDSLCAGTDPNRNWNFHWMEQGTSSRPCTETYGGKKAFSEVETRSFSDFLKTLKGQIKVYLAFHSYSQLLLFPYGHTCQHTYNHDDLQAIGDAAARSLAQRYGTDYTVGNIYDAIYPASGGSMDWAYDTLDIPIAYTYELRPRDGWNGFQLPANQIIPTGEETVDSVVTILKESRRLGYFNTSD
Enzyme Length 304
Uniprot Accession Number P42788
Absorption
Active Site ACT_SITE 259; /note=Proton donor/acceptor; /evidence=ECO:0000250|UniProtKB:P00730
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.17.-
Enzyme Function FUNCTION: Involved in the digestion of the blood meal.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (1); Chain (1); Disulfide bond (1); Metal binding (3); Non-terminal residue (1)
Keywords Carboxypeptidase;Disulfide bond;Hydrolase;Metal-binding;Metalloprotease;Protease;Secreted;Zinc
Interact With
Induction INDUCTION: By blood meal.
Subcellular Location SUBCELLULAR LOCATION: Secreted.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 34,849
Kinetics
Metal Binding METAL 58; /note=Zinc; catalytic; /evidence=ECO:0000250|UniProtKB:P00730; METAL 61; /note=Zinc; catalytic; /evidence=ECO:0000250|UniProtKB:P00730; METAL 184; /note=Zinc; catalytic; /evidence=ECO:0000250|UniProtKB:P00730
Rhea ID
Cross Reference Brenda